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How to get fromPensacola to Charlestonby car, plane, bus, train, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Pensacola to Charleston by car, plane, bus, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Mobile Regional Airport, fly to Charleston International Airport

    best
    1. Drive from Pensacola to Mobile-Airport-MOBcar car
    2. Fly from Mobile Regional Airport (MOB) to Charleston International Airport (CHS)plane plane MOB - CHS
    6h 59m
    $80–400

  2. Fly Pensacola International Airport to Hilton Head Airport, drive

    cheapest
    1. Fly from Pensacola International Airport (PNS) to Hilton Head Airport (HHH)plane plane PNS - HHH
    2. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    9h 29m
    $72–331

  3. Bus, train

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    14h 20m
    $190–338

  4. Drive 532.5 mi

    1. Drive from Pensacola to Charlestoncar car 532.5 mi
    10h 3m
    $98–141

  5. Fly Pensacola International Airport to Charleston International Airport

    1. Fly from Pensacola International Airport (PNS) to Charleston International Airport (CHS)plane plane PNS - CHS
    7h 38m
    $366–1,206

  6. Bus to Destin–Fort Walton Beach Airport, fly to Charleston International Airport

    1. Take the bus from Pensacola to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Charleston International Airport (CHS)plane plane VPS - CHS
    7h 33m
    $159–480

  7. Bus

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    24h 51m
    $169–304

Mobile Regional Airport (MOB) to Charleston International Airport (CHS) flights

Calendar59Weekly Planes
Duration5h 13mAverage Duration
Ticket$68Cheapest Price
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Questions & Answers

Map of how to get from Pensacola to Charleston.ExpandLaunch map view
  • Distance: 588.7 mi
  • Duration: 6h 59m

What companies run services between Pensacola, FL, USA and Charleston, SC, USA?

Delta, American Airlines, and two other airlines fly from Pensacola International Airport (PNS) to Charleston International Airport (CHS) every 2 hours. Alternatively, you can take a bus from Pensacola to Transit Mall via Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 24h 51m.

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