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How to get fromPensacola to Florenceby plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound)

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There are 6 ways to get from Pensacola to Florence by plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Pensacola International Airport

    best
    1. Fly from Pensacola International Airport (PNS) to Florence Regional Airport (FLO)plane plane PNS - FLO
    8h 18m
    $69–337

  2. Bus

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Florencebus bus
    14h 43m
    $150–228

  3. Drive 577.7 mi

    1. Drive from Pensacola to Florencecar car 577.7 mi
    11h 10m
    $106–153

  4. Bus to Destin–Fort Walton Beach Airport, fly

    1. Take the bus from Pensacola to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Florence Regional Airport (FLO)plane plane VPS - FLO
    6h 18m
    $167–491

  5. Bus, train

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the train from Jacksonville to Florence Stationtrain train
    16h 4m
    $196–358

  6. Bus via Sumter

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    4. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus
    17h 7m
    $136–227

Pensacola International Airport (PNS) to Florence Regional Airport (FLO) flights

Calendar9Weekly Planes
Duration6h 58mAverage Duration
Ticket$58Cheapest Price
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Questions & Answers

Map of how to get from Pensacola to Florence.ExpandLaunch map view
  • Distance: 513.1 mi
  • Duration: 8h 18m

What companies run services between Pensacola, FL, USA and Florence, SC, USA?

American Airlines flies from Pensacola International Airport (PNS) to Florence Regional Airport (FLO) once daily. Alternatively, you can take a bus from Pensacola to Florence via Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, Jacksonville, and Florence in around 14h 43m.

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