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How to get fromPensacola to Knoxville Airport (TYS)by car, plane, bus (Greyhound, Flixbus), bus, bus (Flixbus, Greyhound), or train

Find Transport to Knoxville Airport (TYS)

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There are 8 ways to get from Pensacola to Knoxville Airport (TYS) by car, plane, bus (Greyhound, Flixbus), bus, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Mobile Regional Airport, fly

    best
    1. Drive from Pensacola to Mobile-Airport-MOBcar car
    2. Fly from Mobile Regional Airport (MOB) to Mcghee Tyson Airport (TYS)plane plane MOB - TYS
    4h 41m
    $123–718

  2. Drive 503.3 mi

    cheapest
    1. Drive from Pensacola to Knoxville Airport (TYS)car car 503.3 mi
    8h 31m
    $92–133

  3. Bus via Jacksonville

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the bus from Jacksonville to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    40h 57m
    $394–565

  4. Bus to Destin–Fort Walton Beach Airport, fly

    1. Take the bus from Pensacola to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS)plane plane VPS - TYS
    3h 36m
    $192–768

  5. Fly from Pensacola International Airport

    1. Fly from Pensacola International Airport (PNS) to Mcghee Tyson Airport (TYS)plane plane PNS - TYS
    5h 30m
    $99–604

  6. Drive to Northwest Florida Beaches International Airport, fly

    1. Drive from Pensacola to Northwest Florida Beaches International Airport (ECP)car car
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Mcghee Tyson Airport (TYS)plane plane ECP - TYS
    5h 18m
    $118–676

  7. Bus

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Port Authority Bus Terminalbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    44h 36m
    $428–683

  8. Bus, train

    1. Take the bus from Pensacola to Wildwoodbus bus
    2. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    3. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    45h 9m
    $580–1,010

Mobile Regional Airport (MOB) to Mcghee Tyson Airport (TYS) flights

Calendar78Weekly Planes
Duration5h 1mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

Map of how to get from Pensacola to Knoxville Airport (TYS).ExpandLaunch map view
  • Distance: 500 mi
  • Duration: 4h 41m

What companies run services between Pensacola, FL, USA and Knoxville Airport (TYS), USA?

You can take a bus from Pensacola to Knoxville Airport (TYS) via Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, Jacksonville, New York, NY, and Knoxville, TN in around 40h 57m. Alternatively, Southwest Airlines, Delta, and American Airlines fly from Pensacola International Airport (PNS) to Mcghee Tyson Airport (TYS) every 4 hours.

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