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How to get fromPensacola to Louisvilleby car, plane, bus (Greyhound, Amtrak), bus, or bus (Greyhound)

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There are 7 ways to get from Pensacola to Louisville by car, plane, bus (Greyhound, Amtrak), bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Mobile Regional Airport, fly to Louisville International Airport

    best
    1. Drive from Pensacola to Mobile Regional Airport (MOB)car car
    2. Fly from Mobile Regional Airport (MOB) to Louisville International Airport (SDF)plane plane MOB - SDF
    6h 17m
    $123–670

  2. Fly Pensacola International Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Pensacola International Airport (PNS) to Blue Grass Airport (LEX)plane plane PNS - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    7h 27m
    $76–382

  3. Bus

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    19h 27m
    $180–265

  4. Drive  614.3 mi

    1. Drive from Pensacola to Louisvillecar car 614.3 mi
    10h 17m
    $105–152

  5. Bus to Destin–Fort Walton Beach Airport, fly to Louisville International Airport

    1. Take the bus from Pensacola to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF)plane plane VPS - SDF
    5h 11m
    $193–771

  6. Fly Pensacola International Airport to Louisville International Airport

    1. Fly from Pensacola International Airport (PNS) to Louisville International Airport (SDF)plane plane PNS - SDF
    6h 57m
    $105–607

  7. Bus via Preston @ Vim

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    20h 18m
    $188–280

Mobile Regional Airport (MOB) to Louisville International Airport (SDF) flights

Calendar68Weekly Planes
Duration5h 32mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pensacola to Louisville.ExpandLaunch map view
  • Distance: 612.9 mi
  • Duration: 6h 17m

What companies run services between Pensacola, FL, USA and Louisville, KY, USA?

You can take a bus from Pensacola to Louisville, KY via Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, and Nashville in around 19h 27m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Pensacola International Airport (PNS) to Louisville International Airport (SDF) every 4 hours.

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