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How to get fromPensacola to Louisvilleby bus, plane, bus (Greyhound, Amtrak, Flixbus), car, or bus (Greyhound)

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There are 8 ways to get from Pensacola to Louisville by bus, plane, bus (Greyhound, Amtrak, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Destin–Fort Walton Beach Airport, fly to Louisville International Airport

    best
    1. Take the bus from Pensacola to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF)plane plane VPS - SDF
    5h 10m
    $183–611

  2. Fly Pensacola International Airport to Nashville, bus

    cheapest
    1. Fly from Pensacola International Airport (PNS) to Nashville (BNA)plane plane PNS - BNA
    2. Take the bus from Nashville Bus Station to Louisville Bus Stationbus bus
    7h 57m
    $83–371

  3. Bus

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Louisville Bus Stationbus bus
    18h 15m
    $162–280

  4. Drive 614.2 mi

    1. Drive from Pensacola to Louisvillecar car 614.2 mi
    10h 17m
    $113–162

  5. Fly Pensacola International Airport to Louisville International Airport

    1. Fly from Pensacola International Airport (PNS) to Louisville International Airport (SDF)plane plane PNS - SDF
    6h 47m
    $85–447

  6. Fly Pensacola International Airport to Blue Grass Airport, drive

    1. Fly from Pensacola International Airport (PNS) to Blue Grass Airport (LEX)plane plane PNS - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    7h 17m
    $137–723

  7. Bus to Destin–Fort Walton Beach Airport, fly to Blue Grass Airport, drive

    1. Take the bus from Pensacola to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Blue Grass Airport (LEX)plane plane VPS - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 57m
    $235–887

  8. Bus via Preston @ Vim

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    20h 13m
    $188–380

Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF) flights

Calendar56Weekly Planes
Duration3h 32mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Pensacola to Louisville.ExpandLaunch map view
  • Distance: 612.3 mi
  • Duration: 5h 10m

What companies run services between Pensacola, FL, USA and Louisville, KY, USA?

You can take a bus from Pensacola to Louisville Bus Station via Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, and Nashville Bus Station in around 18h 15m. Alternatively, Southwest Airlines, Delta, and American Airlines fly from Pensacola International Airport (PNS) to Louisville International Airport (SDF) every 3 hours.

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