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How to get fromPerdido Key to Port Saint Lucieby plane, bus, car, taxi, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Perdido Key to Port Saint Lucie by plane, bus, car, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pensacola International Airport to Fort Lauderdale–Hollywood International Airport, bus

    best
    1. Fly from Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane PNS - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    5h 59m
    $224–410

  2. Drive to Destin–Fort Walton Beach Airport, fly to Miami International Airport, bus

    cheapest
    1. Drive from Perdido Key to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    3. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    7h 31m
    $100–413

  3. Bus

    1. Take the bus from Pensacola to Ocalabus bus
    2. Take the bus from Ocala, FL to Kissimmee -1471 East Osceola Parkwaybus bus
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    12h 21m
    $217–285

  4. Drive  580.8 mi

    1. Drive from Perdido Key to Port Saint Luciecar car 580.8 mi
    9h 30m
    $106–154

  5. Fly Pensacola International Airport to Miami International Airport, bus

    1. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane plane PNS - MIA
    2. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    6h 14m
    $152–451

  6. Fly Pensacola International Airport to Orlando, bus

    1. Fly from Pensacola International Airport (PNS) to Orlando (MCO)plane plane PNS - MCO
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    6h 33m
    $173–349

  7. Fly Pensacola International Airport to Melbourne International Airport, taxi, bus

    1. Fly from Pensacola International Airport (PNS) to Melbourne International Airport (MLB)plane plane PNS - MLB
    2. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi taxi
    3. Take the bus from Sebastian to Port St Luciebus bus
    8h 32m
    $221–567

  8. Bus via Tallahassee

    1. Take the bus from Pensacola to Tallahasseebus bus
    2. Take the bus from Tallahassee to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Port St Luciebus bus
    16h 48m
    $167–229

Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL) flights

Calendar52Weekly Planes
Duration3h 34mAverage Duration
Ticket$65Cheapest Price
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Comparing Your Travel Options

Map of how to get from Perdido Key to Port Saint Lucie.ExpandLaunch map view
  • Distance: 643.9 mi
  • Duration: 5h 59m

What companies run services between Perdido Key, FL, USA and Port Saint Lucie, FL, USA?

You can take a vehicle from Perdido Key to Fort Pierce via Pensacola, Ocala, Ocala, FL, and Kissimmee -1471 East Osceola Parkway in around 12h 21m.

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