There are 6 ways to get from Perdido Key to Sanibel Island by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Pensacola International Airport to Ft. Myers
best- Fly from Pensacola International Airport (PNS) to Ft. Myers (RSW)plane PNS - RSW
5h 8m$214–620Drive 590.7 mi
cheapest- Drive from Perdido Key to Sanibel Islandcar 590.7 mi
10h 43m$108–156Bus
- Take the bus from Pensacola to Fort Myersbus Houston
12h 5m$208–273Drive to Destin–Fort Walton Beach Airport, fly to Ft. Myers
- Drive from Perdido Key to Destin–Fort Walton Beach Airport (VPS)car
- Fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW)plane VPS - RSW
6h 9m$167–592Drive to Mobile Regional Airport, fly to Ft. Myers
- Drive from Perdido Key to Mobile Regional Airport (MOB)car
- Fly from Mobile Regional Airport (MOB) to Ft. Myers (RSW)plane MOB - RSW
6h 9m$173–604Fly Pensacola International Airport to Miami International Airport, bus
- Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane PNS - MIA
- Take the bus from Miami Airport to Fort Myers 7-11bus
6h 39m$229–570
Pensacola International Airport (PNS) to Ft. Myers (RSW) flights
Comparing Your Travel Options
The cheapest way to get from Perdido Key to Sanibel Island is to drive which costs $100 - $160 and takes 10h 43m.
The fastest way to get from Perdido Key to Sanibel Island is to fly which takes 5h 8m and costs $210 - $650.
No, there is no direct bus from Perdido Key to Sanibel Island. However, there are services departing from Pensacola and arriving at Fort Myers via . The journey, including transfers, takes approximately 12h 5m.
The distance between Perdido Key and Sanibel Island is 475 miles. The road distance is 594.2 miles.
The best way to get from Perdido Key to Sanibel Island without a car is to bus which takes 12h 5m and costs $200 - $280.
It takes approximately 5h 8m to get from Perdido Key to Sanibel Island, including transfers.
Perdido Key to Sanibel Island bus services, operated by Omnibus Express, depart from Pensacola station.
The best way to get from Perdido Key to Sanibel Island is to fly which takes 5h 8m and costs $210 - $650. Alternatively, you can bus, which costs $200 - $280 and takes 12h 5m.
Perdido Key to Sanibel Island bus services, operated by Omnibus Express, arrive at Fort Myers station.
Yes, the driving distance between Perdido Key to Sanibel Island is 594 miles. It takes approximately 10h 43m to drive from Perdido Key to Sanibel Island.
What companies run services between Perdido Key, FL, USA and Sanibel Island, FL, USA?
Delta, American Airlines, and Southwest Airlines fly from Pensacola International Airport (PNS) to Ft. Myers (RSW) every 4 hours. Alternatively, Omnibus Express operates a bus from Pensacola to Fort Myers once daily. Tickets cost $100–140 and the journey takes 11h 8m.
- Website
- delta.com
Flights from Pensacola International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $85–460
Flights from Destin–Fort Walton Beach Airport to Ft. Myers via Atlanta
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $90–490
Flights from Mobile Regional Airport to Ft. Myers via Atlanta
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $95–500
Flights from Pensacola International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $80–420
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Pensacola to Fort Myers
- Ave. Duration
- 11h 8m
- Frequency
- Once daily
- Estimated price
- $100–140
- Schedules at
- Omnibus Express
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Booking & Getting There
There are 4354+ hotels available in Sanibel Island.