There are 10 ways to get from Perugia to Syracuse by bus, plane, train, ferry, night train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Fiumicino International Airport, fly to Catania–Fontanarossa Airport, bus
best- Take the bus from Perugia to Fiumicino Aeroporto T3bus
- Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane FCO - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
5h 57m€42–144Train, ferry, bus via Casoria
- Take the train from Perugia to Roma Terminitrain
- Take the train from Roma Termini to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Catania Centraletrain Re
- Take the bus from Catania Via Archimede to Siracusa - v.le Scala Grecabus
14h 17mBus via Catania
- Take the bus from Perugia to Roma, Autostazione Tiburtinabus 538 / ...
- Take the bus from Roma, Autostazione Tiburtina to Catania Via D'Amicobus
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus
14h 56m€44–84Train, night train, bus
- Take the train from Perugia to Roma Terminitrain
- Take the nighttrain from Roma Termini to Catania Centralenighttrain Ini
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus
16h 56m€89–166Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Perugia to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
6h 28m€43–225Fly Perugia Sant'Egidio Airport to Catania–Fontanarossa Airport, bus
- Fly from Perugia Sant'Egidio Airport (PEG) to Catania–Fontanarossa Airport (CTA)plane PEG - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
4h 16m€45–261Bus to Fiumicino International Airport, fly to Vincenzo Magliocco Airport, train
- Take the bus from Perugia to Fiumicino Aeroporto T3bus
- Fly from Fiumicino International Airport (FCO) to Vincenzo Magliocco Airport (CIY)plane FCO - CIY
- Take the train from Comiso to Siracusatrain
8h 34m€82–375Train, ferry, bus
- Take the train from Perugia to Roma Tiburtinatrain
- Take the train from Roma Tiburtina to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Catania Centraletrain Re
- Take the bus from Catania Via Archimede to Siracusa - v.le Scala Grecabus
15hBus
- Take the bus from Perugia to Roma, Autostazione Tiburtinabus 538 / ...
- Take the bus from Roma, Autostazione Tiburtina to Catania Airportbus
- Take the bus from Catania Airport to Siracusa - Von Platenbus
16h 16m€83–143Drive, car ferry
- Drive from Perugia to Villa S. Giovannicar
- Take the carferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Syracusecar
10h 14m€178–265
Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Perugia to Syracuse is to bus via Catania which costs €40 - €85 and takes 14h 56m.
The fastest way to get from Perugia to Syracuse is to fly and bus which takes 4h 16m and costs €40 - €270.
No, there is no direct bus from Perugia to Syracuse. However, there are services departing from Perugia and arriving at Siracusa - Von Platen via Roma, Autostazione Tiburtina and Catania Via Archimede. The journey, including transfers, takes approximately 14h 56m.
The distance between Perugia and Syracuse is 795 km.
The best way to get from Perugia to Syracuse without a car is to train and ferry and bus via Casoria which takes 14h 17m and costs .
It takes approximately 5h 57m to get from Perugia to Syracuse, including transfers.
Perugia to Syracuse bus services, operated by FlixBus, depart from Perugia station.
Perugia to Syracuse bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Book your Perugia to Syracuse bus tickets online with Omio.
There are 2968+ hotels available in Syracuse.
What companies run services between Perugia, Italy and Syracuse, Italy?
You can take a bus from Perugia to Siracusa - Von Platen via Roma, Autostazione Tiburtina, Catania Via D'Amico, and Catania Via Archimede in around 14h 56m.
- Website
- ryanair.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €21–100
Flights from Perugia Sant'Egidio Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 25m
- When
- Friday and Sunday
- Estimated price
- €45–250
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- €45–110
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Fiumicino International Airport
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- €90–190
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €21–100
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport via Cagliari
- Ave. Duration
- 3h 15m
- When
- Friday and Sunday
- Estimated price
- €21–100
Flights from Fiumicino International Airport to Vincenzo Magliocco Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–270
- Website
- volotea.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- €45–110
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €16–110
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Fiumicino International Airport
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €90–190
- Website
- flyulendo.com
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €22–110
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €35–190
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Perugia to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Perugia to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 2h 12m
- Frequency
- Every 4 hours
- Estimated price
- €18–25
- Website
- Trenitalia
Train from Comiso to Siracusa
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a day
- Estimated price
- €16–23
- Website
- Trenitalia
Train from Perugia to Roma Tiburtina
- Ave. Duration
- 2h 54m
- Frequency
- 5 times a day
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Perugia to Roma Termini
- Ave. Duration
- 2h 20m
- Frequency
- 6 times a week
- Estimated price
- €20–40
- Website
- Trenitalia Intercity
Train from Roma Termini to Napoli Afragola
- Ave. Duration
- 2h 53m
- Frequency
- Once a week
- Estimated price
- €22–45
- Website
- Trenitalia Intercity
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 4h 54m
- Frequency
- Once a week
- Estimated price
- €45–85
- Website
- Trenitalia Intercity
Train from Perugia to Roma Termini
- Ave. Duration
- 2h 20m
- Frequency
- 6 times a week
- Estimated price
- €20–40
- Website
- Trenitalia Intercity
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 1h 29m
- Frequency
- Once daily
- Estimated price
- €16–30
- Website
- Trenitalia Intercity
Train from Perugia to Roma Tiburtina
- Ave. Duration
- 2h 5m
- Frequency
- 6 times a week
- Estimated price
- €20–40
- Website
- Trenitalia Intercity
Train from Roma Tiburtina to Villa S.Giovanni
- Ave. Duration
- 8h 3m
- Frequency
- Once a week
- Estimated price
- €70–130
- Website
- Trenitalia Intercity
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Napoli Afragola
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €29–50
- Website
- Trenitalia Frecce
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 4h 1m
- Frequency
- Every 4 hours
- Estimated price
- €55–100
- Website
- Trenitalia Frecce
Train from Perugia to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- 6 times a week
- Estimated price
- €20–35
- Website
- Trenitalia Frecce
Train from Roma Tiburtina to Villa S.Giovanni
- Ave. Duration
- 6h 2m
- Frequency
- Once daily
- Estimated price
- €90–150
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Napoli Afragola
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- Italo Treno
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 5h 37m
- Frequency
- Once daily
- Estimated price
- €50–85
- Website
- Italo Treno
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Roma Termini to Catania Centrale
- Ave. Duration
- 11h 15m
- Frequency
- Once daily
- Estimated price
- €65–120
- Website
- Trenitalia ICN
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Perugia to Fiumicino Aeroporto T3
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a week
- Estimated price
- €17–26
- Website
- Flixbus
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- €15–23
- Website
- Flixbus
Bus from Perugia to Fiumicino Aeroporto T3
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a week
- Estimated price
- €17–26
- Website
- Flixbus
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- €15–23
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Catania Airport
- Ave. Duration
- 11h 30m
- Frequency
- Twice daily
- Estimated price
- €70–110
- Website
- Flixbus
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - v.le Scala Greca
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €2–9
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - v.le Scala Greca
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €2–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - Von Platen
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +39 075 5009641
- [email protected]
- Website
- sulga.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- €22–26
- Schedules at
- sulga.it
- 2nd Class
- €22–26
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- €22–26
- Schedules at
- sulga.it
- 2nd Class
- €22–26
- Phone
- +39 0972 24590
- [email protected]
- Website
- autolineemoretti.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a week
- Estimated price
- €12–14
- Schedules at
- autolineemoretti.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a week
- Estimated price
- €12–14
- Schedules at
- autolineemoretti.it
- Phone
- +39 0971 54673
- [email protected]
- Website
- autolineeliscio.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 40m
- Frequency
- Twice a week
- Estimated price
- €11–15
- Schedules at
- autolineeliscio.it
Bus from Perugia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 40m
- Frequency
- Twice a week
- Estimated price
- €11–15
- Schedules at
- autolineeliscio.it
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Catania Via D'Amico
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- €30–50
- Schedules at
- autoservizisalemi.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
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