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How to get fromPhiladelphia, PA to Knoxvilleby plane, train, bus, car, or bus (Flixbus)

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There are 7 ways to get from Philadelphia, PA to Knoxville by plane, train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Mcghee Tyson Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    3h 52m
    $228–1,023

  2. Drive 610.5 mi

    cheapest
    1. Drive from Philadelphia, PA to Knoxvillecar car 610.5 mi
    10h 46m
    $112–161

  3. Train, bus

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    15h 17m
    $161–766

  4. Train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    4h 58m
    $202–1,473

  5. Fly Philadelphia International Airport to Asheville Regional Airport, drive

    1. Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane plane PHL - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 47m
    $115–528

  6. Train to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane plane DCA - TYS
    5h 48m
    $272–1,830

  7. Bus

    1. Take the bus from Philadelphia Bus Station to New York Midtownbus bus FlixBus 2602 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    15h 51m
    $206–291

Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights

Calendar74Weekly Planes
Duration3h 44mAverage Duration
Ticket$173Cheapest Price
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Questions & Answers

Map of how to get from Philadelphia, PA to Knoxville.ExpandLaunch map view
  • Distance: 575.2 mi
  • Duration: 3h 52m

What companies run services between Philadelphia, PA, USA and Knoxville, TN, USA?

American Airlines, Allegiant Air, and three other airlines fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) every 2 hours. Alternatively, you can take a vehicle from Philadelphia, PA to Knoxville via Philadelphia Bus Station, New York Midtown, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 15h 51m.

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