There are 6 ways to get from Philadelphia, PA to Knoxville by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Philadelphia International Airport to Mcghee Tyson Airport
best- Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane PHL - TYS
3h 49m$278–1,374Fly Philadelphia International Airport to Asheville Regional Airport, drive
cheapest- Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane PHL - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
5h 45m$110–539Train, bus
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Keystone Service / ...
- Take the bus from New York, NY to Knoxville, TNbus Ny
15h 17m$161–767Drive 610.5 mi
- Drive from Philadelphia, PA to Knoxvillecar 610.5 mi
10h 46m$112–161Train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane BWI - TYS
4h 53m$262–1,824Train to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport
- Take the train from 30th Street Station to Washington Union Stationtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane DCA - TYS
5h 49m$312–2,131
Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Philadelphia, PA to Knoxville is to drive which costs $110 - $170 and takes 10h 46m.
The fastest way to get from Philadelphia, PA to Knoxville is to fly which takes 3h 49m and costs $270 - $1,400.
The distance between Philadelphia, PA and Knoxville is 579 miles. The road distance is 614 miles.
The best way to get from Philadelphia, PA to Knoxville without a car is to train and bus which takes 15h 17m and costs $160 - $800.
It takes approximately 3h 49m to get from Philadelphia, PA to Knoxville, including transfers.
Yes, the driving distance between Philadelphia, PA to Knoxville is 614 miles. It takes approximately 10h 46m to drive from Philadelphia, PA to Knoxville.
There are 318+ hotels available in Knoxville.
What companies run services between Philadelphia, PA, USA and Knoxville, TN, USA?
American Airlines, Allegiant Air, and two other airlines fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) every 3 hours.
- Website
- aa.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $220–1,300
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $230–1,400
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 3h 50m
- When
- Sunday, Thursday, Friday, Monday, Wednesday, and Saturday
- Estimated price
- $190–1,200
Flights from Philadelphia International Airport to Asheville Regional Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $85–500
Flights from Philadelphia International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $85–550
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $220–1,400
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $240–1,400
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Philadelphia International Airport
- Ave. Duration
- 4h 6m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $280–1,600
- Website
- delta.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,500
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,300
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $250–1,400
Flights from Philadelphia International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $110–600
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $280–1,600
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $320–1,700
- Website
- southwest.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 3h 55m
- When
- Saturday
- Estimated price
- $270–1,500
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $180–1,100
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Saturday
- Estimated price
- $280–1,600
- Website
- allegiantair.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h
- When
- Friday and Monday
- Estimated price
- $220–1,300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $50–80
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $70–120
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide





