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How to get fromPhiladelphia to Chicago Bus Stationby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus (Greyhound)

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There are 8 ways to get from Philadelphia to Chicago Bus Station by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Chicago Midway International Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    4h 22m
    $145–408

  2. Fly Philadelphia International Airport to Chicago O'Hare International Airport

    cheapest
    1. Fly from Philadelphia International Airport (PHL) to Chicago O'Hare International Airport (ORD)plane plane PHL - ORD
    4h 48m
    $90–458

  3. Bus

    1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus FlixBus 2601 / ...
    2. Take the bus from Newark Penn Station to Chicago Bus Stationbus bus FlixBus N2641 / ...
    19h 10m
    $143–244

  4. Train via Washington (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train Northeast Regional / ...
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train Floridian
    21h 9m
    $273–1,136

  5. Drive 758.7 mi

    1. Drive from Philadelphia to Chicago Bus Stationcar car 758.7 mi
    12h 28m
    $139–200

  6. Train to Baltimore-Washington International Airport, fly to Chicago Midway International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane plane BWI - MDW
    5h 24m
    $146–913

  7. Bus via Baltimore (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Baltimore Greyhound Garagebus bus Greyhound US0305
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    24h 40m
    $138–282

  8. Train (Amtrak)

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    27h 19m
    $340–700

Philadelphia to Chicago Bus Station by bus

Calendar15Weekly Buses
Duration19h 10mAverage Duration
Ticket$143Cheapest Price
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Questions & Answers

Map of how to get from Philadelphia to Chicago Bus Station.ExpandLaunch map view
  • Distance: 686.5 mi
  • Duration: 4h 22m

What companies run services between Philadelphia, PA, USA and Chicago Bus Station, IL, USA?

Southwest Airlines and Delta fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, you can take a bus from Philadelphia Bus Station to Chicago Bus Station via Newark Penn Station in around 19h 10m.

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