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How to get fromPhiladelphia to Chicago Loopby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound)

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There are 9 ways to get from Philadelphia to Chicago Loop by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Chicago Midway International Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    4h 11m
    $155–378
  2. Bus to Lehigh Valley International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Philadelphia 30th St Station to Allentown Transportation Centerbus bus
    2. Fly from Lehigh Valley International Airport (ABE) to Chicago O'Hare International Airport (ORD)plane plane ABE - ORD
    6h 37m
    $89–370
  3. Bus

    1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus FlixBus 2601 / ...
    2. Take the bus from Newark Penn Station to Chicago Bus Stationbus bus FlixBus N2641 / ...
    19h 10m
    $132–222
  4. Train via Washington (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train Northeast Regional / ...
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train Floridian
    21h
    $253–1,116
  5. Drive 759.1 mi

    1. Drive from Philadelphia to Chicago Loopcar car 759.1 mi
    12h 29m
    $139–201
  6. Fly Philadelphia International Airport to Chicago O'Hare International Airport

    1. Fly from Philadelphia International Airport (PHL) to Chicago O'Hare International Airport (ORD)plane plane PHL - ORD
    4h 33m
    $125–228
  7. Train to Baltimore-Washington International Airport, fly to Chicago Midway International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane plane BWI - MDW
    5h 13m
    $146–913
  8. Bus via Baltimore

    1. Take the bus from Spring Garden to Baltimorebus bus New York / ...
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    22h
    $132–262
  9. Train (Amtrak)

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    27h 10m
    $310–700

Philadelphia to Chicago Loop by bus

Calendar15Weekly Buses
Duration19h 10mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

What companies run services between Philadelphia, PA, USA and Chicago Loop, IL, USA?

Southwest Airlines and Delta fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, you can take a bus from Philadelphia Bus Station to Chicago Bus Station via Newark Penn Station in around 19h 10m.

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