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How to get fromPhiladelphia to Hartsvilleby plane, bus, bus (Greyhound, Flixbus), train (Amtrak), car, taxi, train, or bus (Greyhound)

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There are 10 ways to get from Philadelphia to Hartsville by plane, bus, bus (Greyhound, Flixbus), train (Amtrak), car, taxi, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Myrtle Beach, bus

    best
    1. Fly from Philadelphia International Airport (PHL) to Myrtle Beach (MYR)plane plane PHL - MYR
    2. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    6h 37m
    $165–776

  2. Drive  541.2 mi

    cheapest
    1. Drive from Philadelphia to Hartsvillecar car 541.2 mi
    10h
    $99–143

  3. Bus

    1. Take the bus from Philadelphia Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0320 / ...
    2. Take the bus from Baltimore Downtown Bus Station to Florencebus bus FlixBus N2472
    12h 48m
    $140–200

  4. Train (Amtrak)

    1. Take the train from 30th Street Station to Florence Stationtrain train Palmetto / ...
    13h 46m
    $373–547

  5. Fly to Charlotte Douglas International Airport, bus, taxi

    1. Fly from Philadelphia International Airport (PHL) to Charlotte Douglas International Airport (CLT)plane plane PHL - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the taxi from Camden to Hartsvilletaxi taxi
    7h 21m
    $249–380

  6. Fly to Columbia, bus, taxi

    1. Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane plane PHL - CAE
    2. Take the bus from Columbia, SC to Camdenbus bus
    3. Take the taxi from Camden to Hartsvilletaxi taxi
    8h 13m
    $230–658

  7. Fly to Charleston International Airport, train

    1. Fly from Philadelphia International Airport (PHL) to Charleston International Airport (CHS)plane plane PHL - CHS
    2. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    8h 43m
    $782–1,078

  8. Fly to Raleigh-Durham International Airport, bus

    1. Fly from Philadelphia International Airport (PHL) to Raleigh-Durham International Airport (RDU)plane plane PHL - RDU
    2. Take the bus from Raleigh Bus Station to Florencebus bus
    9h 7m
    $160–489

  9. Fly to Wilmington International Airport, bus

    1. Fly from Philadelphia International Airport (PHL) to Wilmington International Airport (ILM)plane plane PHL - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Fayetteville Bus Stationbus bus
    3. Take the bus from Fayetteville Bus Station to Florencebus bus
    9h 47m
    $193–696

  10. Bus via Raleigh (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Raleigh Bus Stationbus bus Greyhound US0670
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    13h 54m
    $164–230

Philadelphia International Airport (PHL) to Myrtle Beach (MYR) flights

Calendar33Weekly Planes
Duration2h 41mAverage Duration
Ticket$68Cheapest Price
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Comparing Your Travel Options

Map of how to get from Philadelphia to Hartsville.ExpandLaunch map view
  • Distance: 576.8 mi
  • Duration: 6h 37m

What companies run services between Philadelphia, PA, USA and Hartsville, SC, USA?

You can take a bus from Philadelphia Bus Station to Hartsville via Baltimore Downtown Bus Station and Florence in around 12h 48m. Alternatively, Amtrak operates a train from 30th Street Station to Florence Station twice daily. Tickets cost $290–460 and the journey takes 13h 11m.

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