There are 7 ways to get from Philadelphia to Knoxville by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Philadelphia International Airport to Mcghee Tyson Airport
best- Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane PHL - TYS
3h 46m$228–1,023Fly Philadelphia International Airport to Asheville Regional Airport, drive
cheapest- Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane PHL - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
5h 42m$110–538Train, bus via Farragut
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Keystone Service / ...
- Take the bus from New York to Knoxvillebus Nyc
14h 57m$204–849Drive 610.5 mi
- Drive from Philadelphia to Knoxvillecar 610.5 mi
10h 46m$112–161Train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane BWI - TYS
4h 30m$199–1,428Train to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport
- Take the train from 30th Street Station to Washington Union Stationtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane DCA - TYS
5h 28m$260–1,810Train, bus
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Keystone Service / ...
- Take the bus from New York, NY to Knoxville, TNbus Ny
15h 1m$159–759
Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Philadelphia to Knoxville is to drive which costs $110 - $170 and takes 10h 46m.
The fastest way to get from Philadelphia to Knoxville is to fly which takes 3h 46m and costs $220 - $1,100.
The distance between Philadelphia and Knoxville is 578 miles. The road distance is 614 miles.
The best way to get from Philadelphia to Knoxville without a car is to train and bus via Farragut which takes 14h 57m and costs $200 - $850.
It takes approximately 3h 46m to get from Philadelphia to Knoxville, including transfers.
Yes, the driving distance between Philadelphia to Knoxville is 614 miles. It takes approximately 10h 46m to drive from Philadelphia to Knoxville.
There are 315+ hotels available in Knoxville.
What companies run services between Philadelphia, PA, USA and Knoxville, TN, USA?
American Airlines, Allegiant Air, and three other airlines fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) every 2 hours.
- Website
- delta.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 1m
- When
- Sunday, Tuesday, Wednesday, Monday, Thursday, and Friday
- Estimated price
- $160–850
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $260–1,300
Flights from Philadelphia International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $120–600
- Website
- aa.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $170–950
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 3h 43m
- When
- Monday to Saturday
- Estimated price
- $130–750
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $170–1,100
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 3h 56m
- When
- Sunday
- Estimated price
- $190–1,100
Flights from Philadelphia International Airport to Asheville Regional Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $85–500
Flights from Philadelphia International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $90–550
Flights from Philadelphia International Airport to Asheville Regional Airport via Ronald Reagan Washington National Airport
- Ave. Duration
- 3h 54m
- When
- Monday to Friday
- Estimated price
- $85–500
- Website
- southwest.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 4h
- When
- Sunday
- Estimated price
- $220–1,100
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $120–750
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 4h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $230–1,200
- Website
- united.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $170–950
- Website
- allegiantair.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 3m
- When
- Thursday and Sunday
- Estimated price
- $170–950
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $29–60
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $29–60
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $30–470
- First Class
- $150–650
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $20–460
- First Class
- $130–600
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $95–140
- Phone
- +1 615-939-8887
- [email protected]
- Website
- nytnbus.com
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- https://www.nytnbus.com
- Adult One-way
- $95–110
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide





