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How to get fromPhiladelphia to Knoxvilleby plane, train, bus, or car

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There are 8 ways to get from Philadelphia to Knoxville by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Mcghee Tyson Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    3h 43m
    $228–1,073

  2. Fly Philadelphia International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane plane PHL - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 34m
    $105–518

  3. Train, bus via Farragut

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    14h 57m
    $204–849

  4. Drive 610.5 mi

    1. Drive from Philadelphia to Knoxvillecar car 610.5 mi
    10h 46m
    $112–161

  5. Train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    4h 30m
    $209–1,478

  6. Train to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane plane DCA - TYS
    5h 27m
    $270–1,810

  7. Train to Laguardia Airport, fly to Mcghee Tyson Airport

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    5h 56m
    $264–1,683

  8. Train, bus

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    15h 1m
    $159–759

Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights

Calendar59Weekly Planes
Duration3h 2mAverage Duration
Ticket$176Cheapest Price
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Questions & Answers

Map of how to get from Philadelphia to Knoxville.ExpandLaunch map view
  • Distance: 574.9 mi
  • Duration: 3h 43m

What companies run services between Philadelphia, PA, USA and Knoxville, TN, USA?

American Airlines, Allegiant Air, and three other airlines fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) every 4 hours.

Airlines
Train operators
Bus operators

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