There are 10 ways to get from Philadelphia to La Crosse by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Philadelphia International Airport to La Crosse
best- Fly from Philadelphia International Airport (PHL) to La Crosse (LSE)plane PHL - LSE
6h 22m$142–676Bus to Lehigh Valley International Airport, fly to La Crosse
cheapest- Take the bus from Philadelphia 30th St Station to Allentown Transportation Centerbus
- Fly from Lehigh Valley International Airport (ABE) to La Crosse (LSE)plane ABE - LSE
9h 22m$139–489Bus
- Take the bus from Philadelphia Bus Station to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to UW La Crossebus
26h 25m$207–346Train via Washington (Amtrak)
- Take the train from 30th Street Station to Washington Union Stationtrain
- Take the train from Rockville Amtrak to Chicago Union Stationtrain
- Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain
26h 59m$363–1,326Drive 1,039.6 mi
- Drive from Philadelphia to La Crossecar 1,039.6 mi
17h 8m$190–275Fly Philadelphia International Airport to Dane County Regional Airport-Truax Field, bus
- Fly from Philadelphia International Airport (PHL) to Dane County Regional Airport-Truax Field (MSN)plane PHL - MSN
- Take the bus from Madison to UW La Crossebus
8h$210–910Fly Philadelphia International Airport to Minneapolis–Saint Paul International Airport, train
- Fly from Philadelphia International Airport (PHL) to Minneapolis–Saint Paul International Airport (MSP)plane PHL - MSP
- Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain
8h 34m$235–941Fly Philadelphia International Airport to General Mitchell International Airport, train
- Fly from Philadelphia International Airport (PHL) to General Mitchell International Airport (MKE)plane PHL - MKE
- Take the train from Milwaukee to La Crosse Amtrak Stationtrain
8h 36m$215–947Bus via Baltimore
- Take the bus from Philadelphia Bus Station to Baltimore Greyhound Garagebus
- Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to La Crossebus
32h 45m$208–392Train (Amtrak)
- Take the train from 30th Street Station to Chicago Union Stationtrain Cardinal
- Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain Empire Builder / ...
33h 9m$434–878
Philadelphia to La Crosse by train and subway (Amtrak)
Questions & Answers
The cheapest way to get from Philadelphia to La Crosse is to drive which costs $190 - $280 and takes 17h 8m.
The fastest way to get from Philadelphia to La Crosse is to fly which takes 6h 22m and costs $140 - $700.
No, there is no direct bus from Philadelphia station to La Crosse. However, there are services departing from Philadelphia Bus Station and arriving at UW La Crosse via Newark Penn Station, Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 26h 25m.
No, there is no direct train from Philadelphia station to La Crosse station. However, there are services departing from 30th Street Station and arriving at La Crosse Amtrak Station via Union Station, Red Line Center Platform, Rockville Amtrak and Chicago Union Station. The journey, including transfers, takes approximately 26h 59m.
The distance between Philadelphia and La Crosse is 889 miles. The road distance is 1045.7 miles.
The best way to get from Philadelphia to La Crosse without a car is to bus which takes 26h 25m and costs $200 - $350.
It takes approximately 6h 22m to get from Philadelphia to La Crosse, including transfers.
Philadelphia to La Crosse bus services, operated by Flixbus USA, depart from Philadelphia Bus Station.
Philadelphia to La Crosse train services, operated by Amtrak, depart from 30th Street Station.
The best way to get from Philadelphia to La Crosse is to fly which takes 6h 22m and costs $140 - $700. Alternatively, you can bus, which costs $200 - $350 and takes 26h 25m, you could also train via Washington, which costs $360 - $1,400 and takes 26h 59m.
What companies run services between Philadelphia, PA, USA and La Crosse, WI, USA?
American Airlines flies from Philadelphia International Airport (PHL) to La Crosse (LSE) every 4 hours. Alternatively, you can take a bus from Philadelphia Bus Station to UW La Crosse via Newark Penn Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 26h 25m.
- Website
- aa.com
Flights from Philadelphia International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $120–650
Flights from Philadelphia International Airport to La Crosse via Columbus, Chicago O'Hare
- Ave. Duration
- 7h 37m
- When
- Monday to Thursday
- Estimated price
- $130–650
Flights from Philadelphia International Airport to La Crosse via Pittsburgh, Chicago O'Hare
- Ave. Duration
- 7h 42m
- When
- Every day
- Estimated price
- $120–650
Flights from Philadelphia International Airport to La Crosse via Detroit, Chicago O'Hare
- Ave. Duration
- 8h 27m
- When
- Saturday
- Estimated price
- $130–650
Flights from Philadelphia International Airport to La Crosse via Cleveland, Chicago O'Hare
- Ave. Duration
- 9h 13m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Philadelphia International Airport to Dane County Regional Airport-Truax Field
- Ave. Duration
- 2h 31m
- When
- Every day
- Estimated price
- $170–850
Flights from Philadelphia International Airport to Dane County Regional Airport-Truax Field via Charlotte
- Ave. Duration
- 5h 23m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- $230–1,100
Flights from Philadelphia International Airport to Dane County Regional Airport-Truax Field via Reagan Washington
- Ave. Duration
- 5h 24m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–900
Flights from Philadelphia International Airport to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $170–900
Flights from Lehigh Valley International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $85–420
Flights from Lehigh Valley International Airport to La Crosse via Charlotte, Chicago O'Hare
- Ave. Duration
- 9h 16m
- When
- Every day
- Estimated price
- $110–550
Flights from Philadelphia International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 57m
- When
- Every day
- Estimated price
- $160–800
Flights from Philadelphia International Airport to General Mitchell International Airport
- Ave. Duration
- 2h 19m
- When
- Every day
- Estimated price
- $150–800
Flights from Philadelphia International Airport to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $160–800
- Website
- delta.com
Flights from Philadelphia International Airport to Dane County Regional Airport-Truax Field via Detroit
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $170–850
Flights from Philadelphia International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 47m
- When
- Every day
- Estimated price
- $160–800
Flights from Philadelphia International Airport to Minneapolis–Saint Paul International Airport via Detroit
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $160–800
Flights from Philadelphia International Airport to General Mitchell International Airport via Detroit
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $150–800
- Website
- southwest.com
Flights from Philadelphia International Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 4h 41m
- When
- Monday to Wednesday
- Estimated price
- $170–800
Flights from Philadelphia International Airport to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 4h
- When
- Monday to Wednesday
- Estimated price
- $160–800
Flights from Philadelphia International Airport to General Mitchell International Airport via St. Louis
- Ave. Duration
- 4h 35m
- When
- Saturday
- Estimated price
- $210–950
Flights from Philadelphia International Airport to General Mitchell International Airport via Nashville
- Ave. Duration
- 4h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $210–1,000
- Website
- united.com
Flights from Philadelphia International Airport to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $170–900
Flights from Philadelphia International Airport to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $160–800
- Website
- allegiantair.com
Flights from Lehigh Valley International Airport to La Crosse via Punta Gorda
- Ave. Duration
- 8h 6m
- When
- Thursday
- Estimated price
- $180–750
- Website
- suncountry.com
Flights from Philadelphia International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 51m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Train from Rockville Amtrak to Chicago Union Station
- Ave. Duration
- 17h 24m
- Frequency
- Once daily
- Estimated price
- $240–500
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to La Crosse Amtrak Station
- Ave. Duration
- 4h 59m
- Frequency
- 3 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to La Crosse Amtrak Station
- Ave. Duration
- 2h 47m
- Frequency
- 3 times a day
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
Train from Milwaukee to La Crosse Amtrak Station
- Ave. Duration
- 3h 19m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Chicago Union Station
- Ave. Duration
- 27h 10m
- Frequency
- 3 times a week
- Estimated price
- $340–700
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to La Crosse Amtrak Station
- Ave. Duration
- 4h 59m
- Frequency
- 3 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $30–470
- First Class
- $150–650
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 3 hours
- Estimated price
- $12–21
- Schedules at
- flixbus.com
Bus from Newark Penn Station to Chicago Bus Station
- Ave. Duration
- 16h 20m
- Frequency
- Twice daily
- Estimated price
- $130–220
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–24
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 45m
- Frequency
- Every 3 hours
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $14–27
- Website
- https://www.greyhound.com/
Bus from Philadelphia Bus Station to Baltimore Greyhound Garage
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Baltimore Downtown Bus Station to Chicago Bus Station
- Ave. Duration
- 18h 40m
- Frequency
- Twice daily
- Estimated price
- $120–230
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to UW La Crosse
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
Bus from Madison to UW La Crosse
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–55
Bus from Madison to La Crosse
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–55
- Phone
- 570.821.3800
- [email protected]
- Website
- martzbus.com
Bus from Philadelphia 30th St Station to Allentown Transportation Center
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- https://martzbus.com
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- coachusa.com
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- coachusa.com
- Adult
- $25–55
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Philadelphia to La Crosse bus services, operated by Flixbus USA, arrive at Newark Penn Station.
La Crosse is 1h behind Philadelphia. It is currently 7:57 AM in Philadelphia and 6:57 AM in La Crosse.
Philadelphia to La Crosse train services, operated by Amtrak, arrive at Washington Union Station.
Yes, the driving distance between Philadelphia to La Crosse is 1046 miles. It takes approximately 17h 8m to drive from Philadelphia to La Crosse.
Book your Philadelphia to La Crosse train tickets online with Omio.
Book your Philadelphia to La Crosse bus tickets online with Omio.
There are 44+ hotels available in La Crosse.














