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How to get fromPhiladelphia to Lexingtonby plane, train, bus, bus (Greyhound, Flixbus), or car

Find Transport to Lexington

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There are 8 ways to get from Philadelphia to Lexington by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Columbia

    best
    1. Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane plane PHL - CAE
    3h 43m
    $116–529

  2. Drive  624.4 mi

    cheapest
    1. Drive from Philadelphia to Lexingtoncar car 624.4 mi
    10h 51m
    $114–165

  3. Train, bus via Washington

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus Nyc
    14h 36m
    $190–938

  4. Bus

    1. Take the bus from Philadelphia Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0320 / ...
    2. Take the bus from Baltimore, MD to Columbia, SCbus bus Nyc
    15h 1m
    $124–179

  5. Train to Newark Liberty International Airport, fly to Columbia

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Columbia (CAE)plane plane EWR - CAE
    4h 37m
    $118–480

  6. Fly Philadelphia International Airport to Greenville–Spartanburg International Airport, drive

    1. Fly from Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP)plane plane PHL - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Lexingtoncar car
    5h 11m
    $140–780

  7. Fly Philadelphia International Airport to Charleston International Airport, drive

    1. Fly from Philadelphia International Airport (PHL) to Charleston International Airport (CHS)plane plane PHL - CHS
    2. Drive from Charleston-Airport-CHS to Lexingtoncar car
    5h 17m
    $673–934

  8. Train, bus

    1. Take the train from 30th Street Station to Durham Amtrak Stationtrain train Carolinian
    2. Take the bus from Durham to Columbia, SCbus bus Nyc
    17h 38m
    $197–372

Philadelphia International Airport (PHL) to Columbia (CAE) flights

Calendar90Weekly Planes
Duration3h 41mAverage Duration
Ticket$85Cheapest Price
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Comparing Your Travel Options

Map of how to get from Philadelphia to Lexington.ExpandLaunch map view
  • Distance: 539.7 mi
  • Duration: 3h 43m

What companies run services between Philadelphia, PA, USA and Lexington, SC, USA?

American Airlines, United Airlines, and Delta fly from Philadelphia International Airport (PHL) to Columbia (CAE) hourly. Alternatively, you can take a bus from Philadelphia Bus Station to Lexington via Baltimore Downtown Bus Station, HAINES ST & WARNER ST eb, PACA ST & BALTIMORE nb, Pratt St & Howard St, O'Donnell St Cutoff & Travel Center, Baltimore, MD, and Columbia, SC in around 15h 1m.

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