Rome2Rio

How to get fromPhiladelphia to Louisvilleby plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Flixbus, Amtrak)

Find Transport to Louisville

See all options

There are 8 ways to get from Philadelphia to Louisville by plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Louisville International Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Louisville International Airport (SDF)plane plane PHL - SDF
    4h 45m
    $164–957

  2. Fly Philadelphia International Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Philadelphia International Airport (PHL) to Blue Grass Airport (LEX)plane plane PHL - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 43m
    $101–523

  3. Bus

    1. Take the bus from Philadelphia Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    17h 40m
    $143–222

  4. Train, bus (Amtrak)

    1. Take the train from 30th Street Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    24h 35m
    $491–764

  5. Drive  668.3 mi

    1. Drive from Philadelphia to Louisvillecar car 668.3 mi
    11h 27m
    $122–177

  6. Train to Baltimore-Washington International Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    5h 30m
    $155–1,461

  7. Train to Newark Liberty International Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    5h 43m
    $174–869

  8. Bus via Reading

    1. Take the bus from Philadelphia Bus Station to Cincinnatibus bus
    2. Take the bus from Cincinnati to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    21h 30m
    $136–271

Philadelphia to Louisville by bus

Calendar14Weekly Buses
Duration17h 40mAverage Duration
Ticket$143Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Philadelphia to Louisville.ExpandLaunch map view
  • Distance: 589.7 mi
  • Duration: 4h 45m

What companies run services between Philadelphia, PA, USA and Louisville, KY, USA?

American Airlines, Delta, and two other airlines fly from Philadelphia International Airport (PHL) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from Philadelphia Bus Station to Louisville, KY via Indianapolis Union Station in around 17h 40m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There