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How to get fromPhiladelphia to Louisvilleby plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

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There are 8 ways to get from Philadelphia to Louisville by plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Louisville International Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Louisville International Airport (SDF)plane plane PHL - SDF
    4h 43m
    $144–806

  2. Bus via Columbus

    cheapest
    1. Take the bus from Philadelphia Bus Station to Wilson & Ferrell Shell Station - Columbusbus bus Greyhound US0421
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus bus Cleveland
    17h 5m
    $90–192

  3. Train, bus (Amtrak)

    1. Take the train from 30th Street Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    25h 5m
    $250–546

  4. Drive  668.3 mi

    1. Drive from Philadelphia to Louisvillecar car 668.3 mi
    11h 28m
    $122–177

  5. Fly Philadelphia International Airport to Blue Grass Airport, drive

    1. Fly from Philadelphia International Airport (PHL) to Blue Grass Airport (LEX)plane plane PHL - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 35m
    $96–502

  6. Train to Baltimore-Washington International Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    5h 25m
    $135–1,261

  7. Train to Newark Liberty International Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    5h 44m
    $132–699

  8. Bus

    1. Take the bus from Philadelphia Bus Station to Readingbus bus
    2. Take the bus from Reading to Cincinnatibus bus
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    18h 27m
    $93–191

Philadelphia to Louisville by bus

Calendar14Weekly Buses
Duration17h 5mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Philadelphia to Louisville.ExpandLaunch map view
  • Distance: 589.7 mi
  • Duration: 4h 43m

What companies run services between Philadelphia, PA, USA and Louisville, KY, USA?

American Airlines, United Airlines, and two other airlines fly from Philadelphia International Airport (PHL) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from Philadelphia Bus Station to Louisville, KY Bus Station via N Wilson Rd & Ferrell Pl - Columbus in around 17h 5m.

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