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How to get fromPhiladelphia to Santeeby plane, car, train, taxi, bus, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Philadelphia to Santee by plane, car, train, taxi, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Charleston International Airport, drive

    best
    1. Fly from Philadelphia International Airport (PHL) to Charleston International Airport (CHS)plane plane PHL - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    4h 25m
    $663–920

  2. Fly Philadelphia International Airport to Columbia, drive

    cheapest
    1. Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane plane PHL - CAE
    2. Drive from Columbia-Airport-CAE to Santeecar car
    4h 30m
    $98–510

  3. Train, taxi (Amtrak)

    1. Take the train from 30th Street Station to Kingstree Stationtrain train Palmetto / ...
    2. Take the taxi from Kingstree Station to Santeetaxi taxi
    14h 52m
    $300–519

  4. Train, bus

    1. Take the train from 30th Street Station to Baltimore Penn Stationtrain train
    2. Take the bus from Baltimore, MD to Camdenbus bus Nyc
    3. Take the bus from Camden to Orangeburgbus bus
    17h 33m
    $187–823

  5. Drive  601.9 mi

    1. Drive from Philadelphia to Santeecar car 601.9 mi
    10h 25m
    $110–159

  6. Train to Newark Liberty International Airport, fly to Charleston International Airport, drive

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Charleston International Airport (CHS)plane plane EWR - CHS
    3. Drive from Charleston-Airport-CHS to Santeecar car
    5h 23m
    $470–1,161

  7. Bus

    1. Take the bus from Philadelphia Bus Station to Charlotte Bus Stationbus bus Greyhound US0670
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus Greyhound US0644S / ...
    19h 58m
    $189–286

Philadelphia International Airport (PHL) to Charleston International Airport (CHS) flights

Calendar93Weekly Planes
Duration3h 21mAverage Duration
Ticket$102Cheapest Price
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Comparing Your Travel Options

Map of how to get from Philadelphia to Santee.ExpandLaunch map view
  • Distance: 619.5 mi
  • Duration: 4h 25m

What companies run services between Philadelphia, PA, USA and Santee, SC, USA?

You can take a bus from Philadelphia Bus Station to Santee via Charlotte Bus Station and Orangeburg in around 19h 58m.

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