There are 10 ways to get from Philadelphia to West Seneca by plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Philadelphia International Airport to Buffalo Niagara International Airport, line 15 bus
best- Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane PHL - BUF
- Take the bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkwaybus
5h 7m$110–784Drive 338.4 mi
cheapest- Drive from Philadelphia to West Senecacar 338.4 mi
7h 2m$62–90Train (Amtrak)
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Keystone Service / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Stationtrain Empire Service / ...
10h 37m$277–998Bus
- Take the bus from Philadelphia Bus Station to Newark Penn Stationbus Greyhound US0421 / ...
- Take the bus from Newark Penn Station to Buffalobus FlixBus 2686 / ...
11h 25m$75–133Fly Philadelphia International Airport to Rochester, bus
- Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane PHL - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 31m$164–998Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
5h 53m$130–646Train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane BWI - BUF
6h 3m$126–1,288Train to Laguardia Airport, fly to Buffalo Niagara International Airport
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
7h 24m$136–1,393Bus via Scranton (Greyhound)
- Take the bus from Philadelphia Bus Station to Scranton Bus Stationbus Greyhound US0340s
- Take the bus from Scranton Bus Station to Buffalobus Greyhound US0205 / ...
13h 10m$73–115Bus, train
- Take the bus from Market St At 13Th St to Wallenberg Ave Across From Terminalbus 409
- Take the train from Hamilton to Newark Penn Stationtrain Nec
- Take the bus from Newark to Buffalobus
13h 50m$71–297
Philadelphia to West Seneca by bus and foot
Comparing Your Travel Options
The cheapest way to get from Philadelphia to West Seneca is to drive which costs $60 - $90 and takes 7h 2m.
The fastest way to get from Philadelphia to West Seneca is to fly and line 15 bus which takes 5h 7m and costs $110 - $800.
No, there is no direct bus from Philadelphia station to West Seneca. However, there are services departing from Philadelphia Bus Station and arriving at Seneca Street & Maywood Place via Newark Penn Station and Lower Terrace & Adams Mark. The journey, including transfers, takes approximately 11h 25m.
No, there is no direct train from Philadelphia station to West Seneca station. However, there are services departing from 30th Street Station and arriving at Buffalo Depew Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 10h 37m.
The distance between Philadelphia and West Seneca is 304 miles. The road distance is 340.4 miles.
The best way to get from Philadelphia to West Seneca without a car is to train which takes 10h 37m and costs $270 - $1,000.
It takes approximately 5h 7m to get from Philadelphia to West Seneca, including transfers.
Philadelphia to West Seneca bus services, operated by Greyhound USA, depart from Philadelphia Bus Station.
Philadelphia to West Seneca train services, operated by Amtrak, depart from 30th Street Station.
The best way to get from Philadelphia to West Seneca is to train which takes 10h 37m and costs $270 - $1,000. Alternatively, you can bus, which costs $70 - $140 and takes 11h 25m.
What companies run services between Philadelphia, PA, USA and West Seneca, NY, USA?
You can take a train from 30th Street Station to West Seneca via Ny Moynihan Train Hall At Penn Station and Buffalo Depew Station in around 10h 37m. Alternatively, you can take a bus from Philadelphia Bus Station to Seneca Street & Maywood Place via Newark Penn Station, Buffalo, and Lower Terrace & Adams Mark in around 11h 25m.
- Website
- aa.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $100–750
Flights from Philadelphia International Airport to Rochester
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $130–950
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $100–750
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $95–650
- Website
- united.com
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 40m
- When
- Sunday
- Estimated price
- $120–800
Flights from Philadelphia International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–1,000
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–550
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $100–650
- Website
- delta.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $100–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $50–80
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Station
- Ave. Duration
- 8h 1m
- Frequency
- 4 times a day
- Estimated price
- $230–370
- Website
- Amtrak
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $40–70
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $50–80
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
- Phone
- +1 973-275-5555
- Website
- New Jersey Transit
Train from Hamilton to Newark Penn Station
- Ave. Duration
- 1h 7m
- Frequency
- Every 30 minutes
- Estimated price
- $3–22
- Website
- New Jersey Transit
- Website
- NJ Transit: World Cup 2026
- Adult
- $3–22
- Phone
- +1 716-855-7211
- [email protected]
- Website
- NFTA
Bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkway
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $2
- Website
- NFTA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $14–22
- Website
- Greyhound
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $13–20
- Website
- Greyhound
Bus from Philadelphia Bus Station to Scranton Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $26–40
- Website
- Greyhound
Bus from Scranton Bus Station to Buffalo
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Philadelphia Bus Station to Newark Penn Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 3 hours
- Estimated price
- $12–19
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 7h 55m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
- Phone
- +1 973-275-5555
- Website
- New Jersey Transit
Bus from Market St At 13Th St to Wallenberg Ave Across From Terminal
- Ave. Duration
- 2h 35m
- Frequency
- Hourly
- Estimated price
- $7–23
- Website
- New Jersey Transit
- Website
- NJ Transit: World Cup 2026
- Adults
- $7–23
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Newark to Buffalo
- Ave. Duration
- 7h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–240
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $55–230
- Flexible
- $100–240
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Booking & Getting There
Philadelphia to West Seneca bus services, operated by Greyhound USA, arrive at Newark Penn Station.
Philadelphia to West Seneca train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Philadelphia to West Seneca is 340 miles. It takes approximately 7h 2m to drive from Philadelphia to West Seneca.
Book your Philadelphia to West Seneca train tickets online with Omio.
There are 258+ hotels available in West Seneca.
















