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How to get fromPhiladelphia to West Senecaby plane, bus, train (Amtrak), bus (Flixbus, Greyhound), car, train, or bus (Greyhound)

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There are 10 ways to get from Philadelphia to West Seneca by plane, bus, train (Amtrak), bus (Flixbus, Greyhound), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Buffalo Niagara International Airport, line 15 bus

    best
    1. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    2. Take the bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkwaybus bus
    4h 50m
    $117–784

  2. Drive 338.4 mi

    cheapest
    1. Drive from Philadelphia to West Senecacar car 338.4 mi
    7h 2m
    $62–90

  3. Train (Amtrak)

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Stationtrain train Empire Service / ...
    10h 37m
    $187–908

  4. Bus

    1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus FlixBus 2601 / ...
    2. Take the bus from Newark Penn Station to Buffalobus bus FlixBus 2686 / ...
    11h 45m
    $74–145

  5. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    5h 28m
    $105–572

  6. Train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    5h 36m
    $113–1,239

  7. Fly Philadelphia International Airport to Rochester, bus

    1. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 32m
    $134–749

  8. Train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    7h 6m
    $128–1,244

  9. Bus via New York

    1. Take the bus from Philadelphia to New York - Port Authority Bus Terminalbus bus Philadelphia
    2. Take the bus from New York to Buffalobus bus Adt N816 / ...
    11h 59m
    $88–358

  10. Bus via Scranton (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Scranton Bus Stationbus bus Greyhound US0340s
    2. Take the bus from Scranton Bus Station to Buffalobus bus Greyhound US0205 / ...
    13h 10m
    $65–124

Philadelphia to West Seneca by bus and foot

Calendar49Weekly Services
Duration11h 45mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Philadelphia to West Seneca.ExpandLaunch map view
  • Distance: 306.6 mi
  • Duration: 4h 50m

What companies run services between Philadelphia, PA, USA and West Seneca, NY, USA?

You can take a train from 30th Street Station to West Seneca via Ny Moynihan Train Hall At Penn Station and Buffalo Depew Station in around 10h 37m. Alternatively, you can take a bus from Philadelphia Bus Station to Seneca Street & Maywood Place via Newark Penn Station, Buffalo, and Lower Terrace & Adams Mark in around 11h 45m.

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