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How to get fromPhiladelphia to Winston-Salemby plane, bus, train (Amtrak), bus (Greyhound), car, or train

Find Transport to Winston-Salem

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There are 6 ways to get from Philadelphia to Winston-Salem by plane, bus, train (Amtrak), bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Piedmont Triad International Airport, line 1 bus

    best
    1. Fly from Philadelphia International Airport (PHL) to Piedmont Triad International Airport (GSO)plane plane PHL - GSO
    2. Take the bus from Coble Transportation Center to Winston-Salem Transportation Centerbus bus
    4h 9m
    $92–467
  2. Drive  443.9 mi

    cheapest
    1. Drive from Philadelphia to Winston-Salemcar car 443.9 mi
    8h 35m
    $81–117
  3. Train (Amtrak)

    1. Take the train from 30th Street Station to High Pointtrain train Crescent / ...
    10h 54m
    $243–374
  4. Bus (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    12h 55m
    $85–130
  5. Train to Newark Liberty International Airport, fly to Piedmont Triad International Airport

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Piedmont Triad International Airport (GSO)plane plane EWR - GSO
    5h 4m
    $123–480
  6. Fly Philadelphia International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Philadelphia International Airport (PHL) to Charlotte Douglas International Airport (CLT)plane plane PHL - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 24m
    $130–230

Philadelphia to Winston-Salem by train and bus (Amtrak)

Calendar14Weekly Services
Duration10h 54mAverage Duration
Ticket$243Cheapest Price
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Comparing Your Travel Options

What companies run services between Philadelphia, PA, USA and Winston-Salem, NC, USA?

Amtrak operates a train from 30th Street Station to High Point twice daily. Tickets cost $240–370 and the journey takes 9h 11m. Alternatively, Greyhound USA operates a bus from Philadelphia Bus Station to Winston Salem(Trans Center) once daily. Tickets cost $85–130 and the journey takes 12h 55m.

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Need to know: Greyhound

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