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How to get fromPhoenix to Otay Mesaby plane, tram, bus (Greyhound), car, or bus (Flixbus, Greyhound)

Find Transport to Otay Mesa

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There are 4 ways to get from Phoenix to Otay Mesa by plane, tram, bus (Greyhound), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, tram

    best
    1. Fly from Phoenix (PHX) to San Diego International Airport (SAN)plane plane PHX - SAN
    2. Take the tram from Civic Center Station to Iris Avenue Stationtram tram
    3h 57m
    $116–974

  2. Drive 345.8 mi

    cheapest
    1. Drive from Phoenix to Otay Mesacar car 345.8 mi
    6h 4m
    $64–92

  3. Bus

    1. Take the bus from Phoenix Bus Station to San Ysidro Bus Terminalbus bus Greyhound US0851S
    9h 1m
    $95–133

  4. Bus via El Centro

    1. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to El Centro Bus Stopbus bus FlixBus 2054
    2. Take the bus from El Centro Bus Stop to San Ysidro Bus Terminalbus bus Greyhound US0851S
    10h 12m
    $86–138

Phoenix to Otay Mesa by bus and tram

Calendar12Weekly Services
Duration9h 1mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Phoenix to Otay Mesa.ExpandLaunch map view
  • Distance: 330 mi
  • Duration: 3h 57m

What companies run services between Phoenix, AZ, USA and Otay Mesa, CA, USA?

Greyhound USA operates a bus from Phoenix Bus Station to San Ysidro Bus Terminal once daily. Tickets cost $60–120 and the journey takes 8h 25m. Jefferson Lines also services this route 5 times a week.

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