There are 10 ways to get from Phoenixville to Knoxville by bus, plane, train, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 124 bus to Philadelphia International Airport, fly to Mcghee Tyson Airport
best- Take the bus from Plaza at King of Prussia to 30th St & Market St - MBNSbus
- Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane PHL - TYS
5h 30m$353–1,783Drive 599.1 mi
cheapest- Drive from Phoenixville to Knoxvillecar 599.1 mi
11h$103–148Train, bus
- Take the train from Paoli Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain Keystone Service / ...
- Take the bus from New York, NY to Knoxville, TNbus Ny
16h 1m$223–287Line 124 bus, train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport
- Take the bus from Plaza at King of Prussia to 30th St & Market St - MBNSbus
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane BWI - TYS
6h 33m$285–1,929Fly Philadelphia International Airport to Asheville Regional Airport, drive
- Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane PHL - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
7h 26m$128–693Train to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport
- Take the train from 30th Street Station to Washington Union Stationtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane DCA - TYS
7h 22m$325–2,136Line 124 bus, train to Newark Liberty International Airport, fly to Mcghee Tyson Airport
- Take the bus from Plaza at King of Prussia to 30th St & Market St - MBNSbus
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS)plane EWR - TYS
7h 5m$291–1,249Train to Laguardia Airport, fly to Mcghee Tyson Airport
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane LGA - TYS
8h 5m$329–2,096Train, bus via Philadelphia
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain Keystone Service / ...
- Take the bus from New York to Knoxvillebus Nyc
16h 43m$209–862Bus
- Take the bus from Philadelphia Bus Station to New York City Chinatownbus FlixBus 2608
- Take the bus from New York, NY to Knoxville, TNbus Ny
22h 7m$128–159
Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Phoenixville to Knoxville is to drive which costs $100 - $150 and takes 11h.
The fastest way to get from Phoenixville to Knoxville is to line 124 bus and fly which takes 5h 30m and costs $350 - $1,800.
No, there is no direct bus from Phoenixville to Knoxville station. However, there are services departing from Main St & Washington Av and arriving at Knoxville Station Hall of Fame via Plaza at King of Prussia, Philadelphia Bus Station, New York, NY, Walmart and Fountain City Superstop. The journey, including transfers, takes approximately 22h 7m.
The distance between Phoenixville and Knoxville is 607 miles. The road distance is 602.6 miles.
The best way to get from Phoenixville to Knoxville without a car is to train and bus which takes 16h 1m and costs $220 - $290.
It takes approximately 5h 30m to get from Phoenixville to Knoxville, including transfers.
Phoenixville to Knoxville bus services, operated by Flixbus USA, depart from Philadelphia Bus Station.
Phoenixville to Knoxville bus services, operated by Flixbus USA, arrive at New York City Chinatown station.
Yes, the driving distance between Phoenixville to Knoxville is 603 miles. It takes approximately 11h to drive from Phoenixville to Knoxville.
There are 320+ hotels available in Knoxville.
What companies run services between Phoenixville, PA, USA and Knoxville, TN, USA?
You can take a bus from Main St & Washington Av to Knoxville Station Hall of Fame via Plaza at King of Prussia, 13th St & Market St - MBFS, Philadelphia Bus Station, New York, NY, Knoxville, TN, Walmart, and Fountain City Superstop in around 22h 7m.
- Website
- delta.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $360–1,900
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $250–1,400
Flights from Philadelphia International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $130–750
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $290–1,600
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $320–1,700
Flights from Newark Liberty International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Newark Liberty International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,300
Flights from Laguardia Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 19m
- When
- Every day
- Estimated price
- $240–1,400
Flights from Laguardia Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $290–1,500
- Website
- aa.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $290–1,700
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $310–1,800
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $210–1,300
Flights from Philadelphia International Airport to Asheville Regional Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $100–650
Flights from Philadelphia International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $100–650
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $230–1,400
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $240–1,500
Flights from Newark Liberty International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 30m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $200–1,100
Flights from Laguardia Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- $240–1,400
Flights from Laguardia Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $250–1,400
Flights from Laguardia Airport to Mcghee Tyson Airport via Ronald Reagan Washington National Airport
- Ave. Duration
- 4h 34m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,400
- Website
- united.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $290–1,700
Flights from Newark Liberty International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Newark Liberty International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Laguardia Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $240–1,400
- Website
- allegiantair.com
Flights from Philadelphia International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h
- When
- Friday and Monday
- Estimated price
- $290–1,700
Flights from Newark Liberty International Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 3m
- When
- Friday, Wednesday, and Monday
- Estimated price
- $190–1,100
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $200–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Paoli Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 2h 9m
- Frequency
- Every 2 hours
- Estimated price
- $60–95
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $70–120
- Website
- Amtrak
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $40–70
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $45–80
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $45–80
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
- Phone
- +1 215-580-7800
- Website
- SEPTA
Bus from Plaza at King of Prussia to 30th St & Market St - MBNS
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Bus from Plaza at King of Prussia to 30th St & Market St - MBNS
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Bus from Plaza at King of Prussia to 30th St & Market St - MBNS
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Philadelphia Bus Station to New York City Chinatown
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- $23–35
- Schedules at
- Flixbus USA
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