There are 7 ways to get from Piazza del Duomo to Santo Spirito by train (Trenitalia), bus, car, plane, train, or rideshare
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Milano Rogoredo to Firenze S.M.N.train Fr
2h 28m€32–92Rideshare
cheapest- Take the rideshare from Milan to Florence301.6 km
4h 5m€17Bus
- Take the bus from Milano, San Donato M3 to Florencebus N1550
5h 38m€27–47Drive 302.9 km
- Drive from Piazza del Duomo to Santo Spiritocar 302.9 km
3h 2m€48–69Fly from Milan Linate Airport
- Fly from Milan Linate Airport (LIN) to Florence Peretola Airport (FLR)plane LIN - FLR
4h 19m€104–274Train via Rho-Fiera Milano
- Take the train from Rho-Fiera Milano to Florence Santa Maria Novellatrain 9963 / ...
3h 55m€42–83Train to Milano Malpensa Airport, fly
- Take the train from Milano Cadorna to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane MXP - FLR
5h 44m€96–197
Piazza del Duomo to Santo Spirito by foot, subway, and train
Questions & Answers
The cheapest way to get from Piazza del Duomo to Santo Spirito is to rideshare which costs €17 and takes 4h 5m.
The fastest way to get from Piazza del Duomo to Santo Spirito is to train which takes 2h 28m and costs €30 - €95.
No, there is no direct bus from Piazza del Duomo to Santo Spirito. However, there are services departing from duomo m1 m3 and arriving at Florence via Milano, San Donato M3. The journey, including transfers, takes approximately 5h 38m.
No, there is no direct train from Piazza del Duomo to Santo Spirito. However, there are services departing from Duomo M3 and arriving at Firenze S.M.N. via Milano Rogoredo. The journey, including transfers, takes approximately 2h 28m.
The distance between Piazza del Duomo and Santo Spirito is 303 km. The road distance is 302.9 km.
The best way to get from Piazza del Duomo to Santo Spirito without a car is to train which takes 2h 28m and costs €30 - €95.
It takes approximately 2h 28m to get from Piazza del Duomo to Santo Spirito, including transfers.
Piazza del Duomo to Santo Spirito bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Piazza del Duomo to Santo Spirito train services, operated by Trenitalia Frecce, depart from Milano Rogoredo station.
The best way to get from Piazza del Duomo to Santo Spirito is to train which takes 2h 28m and costs €30 - €95. Alternatively, you can bus, which costs €27 - €50 and takes 5h 38m, you could also fly, which costs €100 - €280 and takes 4h 19m.
What companies run services between Piazza del Duomo, Lombardy, Italy and Santo Spirito, Tuscany, Italy?
Trenitalia Frecce operates a train from Milano Rogoredo to Firenze S.M.N. every 30 minutes. Tickets cost €40–90 and the journey takes 1h 45m. Two other operators also service this route. Alternatively, FlixBus operates a bus from Milano, San Donato M3 to Florence 6 times a week. Tickets cost €25–45 and the journey takes 3h 50m.
- Website
- ita-airways.com
Flights from Milan Linate Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €140–250
Flights from Milan Linate Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €100–390
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Friday to Sunday
- Estimated price
- €200–700
Flights from Milan Linate Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 5h 10m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- €170–650
Flights from Milano Malpensa Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- €90–310
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Monday, Wednesday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- €150–550
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Monday
- Estimated price
- €130–450
- Website
- swiss.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- €90–310
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Monday
- Estimated price
- €130–450
- Website
- austrian.com
Flights from Milan Linate Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €140–250
Flights from Milan Linate Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €100–390
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Monday
- Estimated price
- €130–450
- Website
- lufthansa.com
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Friday to Sunday
- Estimated price
- €200–700
Flights from Milan Linate Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 5h 10m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- €170–650
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Monday, Wednesday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- €150–550
- Website
- airdolomiti.it
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Friday to Sunday
- Estimated price
- €200–700
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Monday, Wednesday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- €150–550
- Website
- polarair.ru
Flights from Milan Linate Airport to Florence Peretola Airport via Elba Island
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €45–550
- Website
- flexflight.dk
Flights from Milan Linate Airport to Florence Peretola Airport via Elba Island
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €45–550
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 1h 45m
- Frequency
- Every 30 minutes
- Estimated price
- €40–90
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 1h 53m
- Frequency
- 4 times a day
- Estimated price
- €35–75
- Website
- Italo Treno
Train from Rho-Fiera Milano to Florence Santa Maria Novella
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- €40–80
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Rogoredo to Firenze S.M.N.
- Ave. Duration
- 3h 26m
- Frequency
- 3 times a day
- Estimated price
- €30–65
- Website
- Trenitalia Intercity
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Milano Cadorna to Malpensa Aeroporto T1
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Milano, San Donato M3 to Florence
- Ave. Duration
- 3h 50m
- Frequency
- 6 times a week
- Estimated price
- €25–45
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar
Rideshare from Milan to Florence
- Ave. Duration
- 3h 52m
- Frequency
- Hourly
- Estimated price
- €17
- Schedules at
- BlaBlaCar
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More Questions & Answers
Piazza del Duomo to Santo Spirito bus services, operated by FlixBus, arrive at Florence station.
Piazza del Duomo to Santo Spirito train services, operated by Trenitalia Frecce, arrive at Firenze S.M.N. station.
Yes, the driving distance between Piazza del Duomo to Santo Spirito is 303 km. It takes approximately 3h 2m to drive from Piazza del Duomo to Santo Spirito.
There are 8447+ hotels available in Santo Spirito.
Check out Blablacar's carpooling service for rideshare options between Piazza del Duomo and Santo Spirito. A great option if you don't have a driver's licence or want to avoid public transport.






















