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How to get fromPicayune to Knoxvilleby taxi, plane, train, bus, shuttle, or car

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There are 4 ways to get from Picayune to Knoxville by taxi, plane, train, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Picayune to Gulfport-Biloxi Regional Airport (GPT)taxi taxi
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS)plane plane GPT - TYS
    4h 58m
    $307–1,003

  2. Drive 550 mi

    cheapest
    1. Drive from Picayune to Knoxvillecar car 550 mi
    8h 59m
    $101–145

  3. Train, bus, shuttle, drive

    1. Take the train from Picayune Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Take the bus from Charlotte to Boonebus bus
    3. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Knoxvillecar car
    27h 40m
    $504–769

  4. Train, bus, taxi, shuttle, drive

    1. Take the train from Picayune Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take the taxi from ASU Peacock Hall Boone to Black Bear Resorttaxi taxi
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Chilhowee at Holstoncar car
    27h 42m
    $601–894

Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS) flights

Calendar60Weekly Planes
Duration5h 14mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from Picayune to Knoxville.ExpandLaunch map view
  • Distance: 531.7 mi
  • Duration: 4h 58m

What companies run services between Picayune, MS, USA and Knoxville, TN, USA?

There is no direct connection from Picayune to Knoxville. However, you can take the taxi to Gulfport-Biloxi Regional Airport (GPT) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from Picayune Amtrak Station to Knoxville via Charlotte Amtrak Station, Parkwood Station, CTC Station, Transit Center- Bay E, 4th St & Graham St, Charlotte, Boone, Boone, Black Bear Resort, and Hot Springs in around 27h 40m.

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