There are 7 ways to get from Pisa to Brindisi by plane, bus, train or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Recommended option
Fly from Pisa • 1h 48m
6 alternative options
Bus to Florence, fly • 6h 3m
Train via Rome • 9h 7m
Train • 9h 33m
Bus via Livorno • 13h 42m
Bus • 15h 25m
Drive • 8h 50m
Pisa to Brindisi by train
Questions & Answers
The cheapest way to get from Pisa to Brindisi is to bus via Livorno which costs €60 - €140 and takes 13h 42m.
The fastest way to get from Pisa to Brindisi is to fly which takes 1h 48m and costs €21 - €250.
No, there is no direct bus from Pisa to Brindisi. However, there are services departing from Pisa and arriving at Brindisi via Bari. The journey, including transfers, takes approximately 15h 25m.
No, there is no direct train from Pisa to Brindisi. However, there are services departing from Pisa Centrale and arriving at Brindisi via Firenze S.M.N. and Roma Termini. The journey, including transfers, takes approximately 9h 7m.
The distance between Pisa and Brindisi is 709 km. The road distance is 965.3 km.
The best way to get from Pisa to Brindisi without a car is to train via Rome which takes 9h 7m and costs €55 - €270.
It takes approximately 1h 48m to get from Pisa to Brindisi, including transfers.
Pisa to Brindisi bus services, operated by FlixBus, depart from Pisa station.
Pisa to Brindisi train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Brindisi is to fly which takes 1h 48m and costs €21 - €250. Alternatively, you can train via Rome, which costs €55 - €270 and takes 9h 7m, you could also bus via Livorno, which costs €60 - €140 and takes 13h 42m.
- Distance: 709.5 km
- Duration: 1h 48m
What companies run services between Pisa, Italy and Brindisi, Italy?
Ryanair flies from Pisa to Brindisi once daily. Alternatively, you can take a train from Pisa to Brindisi via Firenze S.M.N. and Roma Termini in around 9h 7m.
- Website
- alitalia.com
Flights from Florence to Brindisi via Rome
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- €75 - €280
- Website
- ryanair.com
Flights from Pisa to Brindisi
- Ave. Duration
- 1h 25m
- When
- Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- €20 - €370
- Website
- swiss.com
Flights from Florence to Brindisi via Zurich
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- €310 - €900
The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.
Contact Details
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €6 - €12
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €10 - €12
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 46m
- Frequency
- Every 4 hours
- Estimated price
- €20 - €35
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €32 - €35
Frequently asked questions
Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.
Contact Details
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €21 - €75
- Website
- https://www.trenitalia.com/en/frecce.html
- Super Economy
- €21 - €29
- Base Standard
- €40 - €55
- Base Premium
- €50 - €75
Train from Roma Termini to Brindisi
- Ave. Duration
- 5h
- Frequency
- 3 times a day
- Estimated price
- €35 - €95
- Website
- https://www.trenitalia.com/en/frecce.html
- Super Economy
- €35 - €50
- Base Standard
- €55 - €80
- Base Premium
- €65 - €95
Train from Firenze S.M.N. to Brindisi
- Ave. Duration
- 7h 11m
- Frequency
- Once daily
- Estimated price
- €55 - €170
- Website
- https://www.trenitalia.com/en/frecce.html
- Super Economy
- €55 - €80
- Base Standard
- €95 - €130
- Base Premium
- €110 - €170
Private train company Italotreno operates high-speed trains in Italy on the same tracks as Trenitalia. The routes service 21 stations across the country, including popular routes Milan-Florence, Rome-Venice and Bologna-Naples. Choose from four classes of service, all with free Wi-Fi: Smart, Comfort, Prima and Club Executive. Italo also operates Italobus – an integrated train-bus service that takes passengers from the main train stations to other Italian cities.
Contact Details
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Stazione Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 37m
- Frequency
- Hourly
- Estimated price
- €45 - €60
- Website
- https://www.italotreno.it/en
- Smart Economy
- €45 - €60
- Smart Flex
- €45 - €60
- Phone
- +43 51717
- Website
- nightjet.com
Train from Stazione Santa Maria Novella to Roma Termini
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a week
- Estimated price
- €35 - €160
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €130 - €160
- Seating Carriage
- €35 - €50
- Couchette Carriage
- €85 - €110
.jpg)
Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).
Contact Details
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 35m
- Frequency
- 6 times a week
- Estimated price
- €17 - €23
- Website
- https://www.trenitalia.com/
- 2nd Class
- €17 - €23
- Phone
- +352 26 58 57 1
- info@flibco.com
- Website
- flibco.com
Bus from Pisa International Airport to Florence Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €13 - €18
- Website
- https://www.flibco.com/en
- Phone
- +39 0835 522250
- biglietteria@chiruzzi.it
- Website
- chiruzzi.com
Bus from Livorno to Bari
- Ave. Duration
- 9h 55m
- Frequency
- Twice a week
- Estimated price
- €55 - €80
- Schedules at
- chiruzzi.com
One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.de
Bus from Bari to Brindisi
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €11 - €16
- Website
- https://www.flixbus.co.uk
Bus from Pisa to Bari
- Ave. Duration
- 12h 55m
- Frequency
- 5 times a week
- Estimated price
- €65 - €90
- Website
- https://www.flixbus.co.uk
Frequently asked questions
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Bari Central Train Station to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- €17 - €23
- Website
- https://marinobus.it/en/
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Bari Via Giuseppe Capruzzi to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- €6 - €10
- Website
- https://www.itabus.it/en/home
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Travel inspiration and top planning tips for getting around Italy.
Read the travel guide5 incredible day trips from Florence by train
Within 90 minutes, you could be exploring regions as stunning as Emilia-Romagna, Umbria and the Veneto.
Read the travel guideHow to get from Florence to Rome
We show you the quickest, cheapest and easiest routes between the Italian cities
Read the travel guideWant to know more about Flixbus?
Rome2Rio’s guide has all the details
Read the travel guideMore Questions & Answers
Pisa to Brindisi bus services, operated by FlixBus, arrive at Brindisi station.
Pisa to Brindisi train services, operated by Trenitalia Frecce, arrive at Brindisi station.
Yes, the driving distance between Pisa to Brindisi is 965 km. It takes approximately 8h 50m to drive from Pisa to Brindisi.
Book your Pisa to Brindisi train tickets online with Omio.
Book your Pisa to Brindisi bus tickets online with FlixBus.
There are 913+ hotels available in Brindisi. Prices start at €34 per night.