There are 9 ways to get from Pisa to Heidelberg by bus, plane, train, train (Trenitalia), car, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Florence Peretola Airport, fly to Frankfurt, train
best- Take the bus from Pisa International Airport to Florence Airportbus
- Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane FLR - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
6h 5m€143–362Bus via Milan
cheapest- Take the bus from Pisa to Milanbus FlixBus 507
- Take the bus from Milan to Heidelberg Pre Waypointbus FlixBus N07 / ...
16h 39m€86–133Train
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
- Take the train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhoftrain S3 / ...
12h€158–303Bus
- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Karlsruhe Central Bus Stationbus
- Take the bus from Karlsruhe central train station to Heidelberg Pre Waypointbus 198 / ...
15h 27m€123–180Drive 858.3 km
- Drive from Pisa to Heidelbergcar 858.3 km
8h 27m€139–201Train, train to Bologna Guglielmo Marconi Airport, fly to Frankfurt
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane BLQ - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
7h 16m€123–384Fly Pisa International Airport to Cologne Bonn Airport, train
- Fly from Pisa International Airport (PSA) to Cologne Bonn Airport (CGN)plane PSA - CGN
- Take the train from Köln Messe/Deutz Bf to Mannheim, Hauptbahnhoftrain
4h 34m€95–304Bus to Florence Peretola Airport, fly to Munich International Airport, train
- Take the bus from Pisa International Airport to Florence Airportbus
- Fly from Florence Peretola Airport (FLR) to Munich International Airport (MUC)plane FLR - MUC
- Take the train from München Hbf to Mannheim, Hauptbahnhoftrain
8h 50m€168–474Train, night train
- Take the train from Pisa Centrale to Zuerich Hbtrain Ec
- Take the nighttrain from Zuerich Hb to Heidelberg Hbfnighttrain Nj
14h 7m€141–263
Pisa to Heidelberg by train
Comparing Your Travel Options
The cheapest way to get from Pisa to Heidelberg is to bus via Milan which costs €85 - €140 and takes 16h 39m.
The fastest way to get from Pisa to Heidelberg is to fly and train which takes 4h 34m and costs €90 - €310.
No, there is no direct bus from Pisa to Heidelberg. However, there are services departing from Pisa and arriving at Heidelberg Pre Waypoint via Florence Villa Constanza Bus Station and Karlsruhe central train station. The journey, including transfers, takes approximately 15h 27m.
No, there is no direct train from Pisa to Heidelberg. However, there are services departing from Pisa Centrale and arriving at Heidelberg, Hauptbahnhof via Firenze S.M.N., Milano Centrale and Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 12h.
The distance between Pisa and Heidelberg is 893 km. The road distance is 858.3 km.
The best way to get from Pisa to Heidelberg without a car is to train which takes 12h and costs €150 - €310.
It takes approximately 6h 5m to get from Pisa to Heidelberg, including transfers.
Pisa to Heidelberg bus services, operated by FlixBus, depart from Pisa station.
Pisa to Heidelberg train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Heidelberg is to train which takes 12h and costs €150 - €310. Alternatively, you can bus, which costs €120 - €180 and takes 15h 27m.
What companies run services between Pisa, Italy and Heidelberg, Germany?
You can take a train from Pisa Centrale to Heidelberg, Hauptbahnhof via Firenze S.M.N., Milano Centrale, Karlsruhe Hbf, and Karlsruhe Hauptbahnhof in around 12h. Alternatively, you can take a bus from Pisa to Heidelberg Pre Waypoint via Florence Villa Constanza Bus Station and Karlsruhe central train station in around 15h 27m.
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €110–470
Flights from Florence Peretola Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €150–490
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €130–420
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 3h 38m
- When
- Monday to Saturday
- Estimated price
- €130–430
Flights from Florence Peretola Airport to Munich International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €170–550
Flights from Florence Peretola Airport to Munich International Airport via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–300
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €150–470
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €130–420
Flights from Florence Peretola Airport to Munich International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €170–550
- Website
- swiss.com
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 25m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €70–280
Flights from Florence Peretola Airport to Munich International Airport via Zurich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €90–370
- Website
- austrian.com
Flights from Florence Peretola Airport to Munich International Airport via Vienna
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €90–390
- Website
- condor.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
- Website
- eurowings.com
Flights from Pisa International Airport to Cologne Bonn Airport
- Ave. Duration
- 1h 40m
- When
- Friday and Sunday
- Estimated price
- €80–240
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 4 hours
- Estimated price
- €9–21
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Köln Messe/Deutz Bf to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €40–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 45m
- Frequency
- Hourly
- Estimated price
- €55–130
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 3 times a day
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 3 times a day
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Köln Messe/Deutz Bf to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- 5 times a day
- Estimated price
- €26–50
- Website
- Nederlandse Spoorwegen (NS)
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 44m
- Frequency
- Once daily
- Estimated price
- €35–70
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 39 min
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 17m
- Frequency
- Once daily
- Estimated price
- €110–170
- Website
- Trenitalia Eurocity
- 1st Class
- €110–170
- 2nd Class
- €110–150
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
Train from Pisa Centrale to Zuerich Hb
- Ave. Duration
- 9h 5m
- Frequency
- Twice a week
- Estimated price
- €110–170
- Website
- Trenitalia Eurocity
- 1st Class
- €120–170
- 2nd Class
- €110–150
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhof
- Ave. Duration
- 36 min
- Frequency
- Every 30 minutes
- Estimated price
- €10–45
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Heidelberg, Hauptbahnhof
- Ave. Duration
- 42 min
- Frequency
- 3 times a day
- Estimated price
- €17–26
- Website
- Österreichische Bundesbahnen
- Phone
- +49 221 800 20 80
- [email protected]
- Website
- MSM Partyzug
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 3h 16m
- Frequency
- Once a week
- Schedules at
- MSM Partyzug
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Zuerich Hb to Heidelberg Hbf
- Ave. Duration
- 4h 2m
- Frequency
- Twice daily
- Estimated price
- €26–95
- Website
- Nightjet
- Sleeper Carriage
- €92–95
- Couchette Carriage
- €55–70
- Seating Carriage
- €26–32
- Phone
- +352 50 55 62 63 10
- [email protected]
- Website
- Flibco
Bus from Pisa International Airport to Florence Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €12–22
- Website
- Flibco
Bus from Pisa International Airport to Florence Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €12–22
- Website
- Flibco
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Website
- Flixbus
Bus from Karlsruhe central train station to Heidelberg Pre Waypoint
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €4–8
- Website
- Flixbus
Bus from Pisa to Milan
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- €35–55
- Website
- Flixbus
Bus from Milan to Heidelberg Pre Waypoint
- Ave. Duration
- 8h 54m
- Frequency
- 3 times a day
- Estimated price
- €50–80
- Website
- Flixbus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Karlsruhe Central Bus Station
- Ave. Duration
- 11h 15m
- Frequency
- Once a week
- Estimated price
- €110–160
- Website
- Onebus
Want to know more about travelling around Germany
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Booking & Getting There
Pisa to Heidelberg bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Heidelberg train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Heidelberg is 858 km. It takes approximately 8h 27m to drive from Pisa to Heidelberg.
Book your Pisa to Heidelberg train tickets online with Omio.
Book your Pisa to Heidelberg bus tickets online with Omio.
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