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How to get fromPisa to Iserniaby train (Trenitalia), bus, car, plane, or train

Find Transport to Isernia

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There are 8 ways to get from Pisa to Isernia by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Pisa Centrale to Roma Tiburtinatrain train Fa / ...
    2. Take the train from Roma Tiburtina to Iserniatrain train Re
    5h 23m
    €68–107

  2. Bus, train

    cheapest
    1. Take the bus from Pisa to Cassinobus bus
    2. Take the train from Cassino to Iserniatrain train Re
    9h 8m
    €37–52

  3. Bus

    1. Take the bus from Pisa to Roma, Autostazione Tiburtinabus bus N1508 / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus Rome Tiburtina
    7h 55m
    €38–67

  4. Drive  507.4 km

    1. Drive from Pisa to Iserniacar car 507.4 km
    5h 1m
    €83–119

  5. Fly Pisa International Airport to Naples Airport, train

    1. Fly from Pisa International Airport (PSA) to Naples Airport (NAP)plane plane PSA - NAP
    2. Take the train from Caserta to Iserniatrain train
    6h 56m
    €86–269

  6. Train via Rome (Trenitalia)

    1. Take the train from Pisa Centrale to Roma Terminitrain train Fb / ...
    2. Take the train from Roma Termini to Iserniatrain train Re
    6h 4m
    €58–112

  7. Bus to Florence Peretola Airport, fly to Fiumicino International Airport, train

    1. Take the bus from Pisa International Airport to Florence Airportbus bus
    2. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane plane FLR - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    6h 56m
    €98–262

  8. Fly Pisa International Airport to Bari Karol Wojtyła Airport, train, bus

    1. Fly from Pisa International Airport (PSA) to Bari Karol Wojtyła Airport (BRI)plane plane PSA - BRI
    2. Take the train from Bari Centrale to Foggiatrain train
    3. Take the bus from Foggia to Iserniabus bus
    7h 1m
    €68–257

Pisa to Isernia by train (Trenitalia)

Calendar6Weekly Trains
Duration5h 23mAverage Duration
Ticket€68Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pisa to Isernia.ExpandLaunch map view
  • Distance: 516.6 km
  • Duration: 5h 23m

What companies run services between Pisa, Italy and Isernia, Italy?

You can take a train from Pisa Centrale to Isernia via Roma Tiburtina in around 5h 23m. Alternatively, you can take a bus from Pisa to Isernia via Roma, Autostazione Tiburtina in around 7h 55m.

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