There are 6 ways to get from Pisa to Lyon by plane, train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Pisa International Airport (PSA) to Lyon–Saint Exupéry Airport (LYS)plane PSA - LYS
4h 46m€102–306Bus
cheapest- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Lyonbus 1501 / ...
13h 15m€43–102Train
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
9h 16m€89–163Drive 624.6 km
- Drive from Pisa to Lyoncar 624.6 km
6h 29m€101–146Train via Turin
- Take the train from Pisa Centrale to Genova P.Za Principetrain Fb / ...
- Take the train from Genova P.Za Principe to Torino Lingottotrain
- Take the train from Torino Porta Susa to Lyon Part Dieutrain Fr
9h 24m€69–175Bus via Turin
- Take the bus from Pisa to Turinbus 544
- Take the bus from Turin Corso Vittorio Emanuele II to Lyon Lyon Perrache Bus Stationbus Itabus
15h€64–100
Pisa to Lyon by train
Comparing Your Travel Options
The cheapest way to get from Pisa to Lyon is to bus which costs €40 - €110 and takes 13h 15m.
The fastest way to get from Pisa to Lyon is to fly which takes 4h 46m and costs €100 - €310.
No, there is no direct bus from Pisa to Lyon. However, there are services departing from Pisa and arriving at Lyon via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 13h 15m.
No, there is no direct train from Pisa to Lyon. However, there are services departing from Pisa Centrale and arriving at Lyon Part Dieu via Firenze S.M.N. and Milano Centrale. The journey, including transfers, takes approximately 9h 16m.
The distance between Pisa and Lyon is 498 km. The road distance is 624.6 km.
The best way to get from Pisa to Lyon without a car is to train which takes 9h 16m and costs €85 - €170.
It takes approximately 4h 46m to get from Pisa to Lyon, including transfers.
Pisa to Lyon bus services, operated by FlixBus, depart from Pisa station.
Pisa to Lyon train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Lyon is to fly which takes 4h 46m and costs €100 - €310. Alternatively, you can train, which costs €85 - €170 and takes 9h 16m, you could also bus, which costs €40 - €110 and takes 13h 15m.
What companies run services between Pisa, Italy and Lyon, France?
Air Dolomiti, Lufthansa, and three other airlines fly from Pisa International Airport (PSA) to Lyon–Saint Exupéry Airport (LYS) twice daily. Alternatively, you can take a train from Pisa Centrale to Lyon Part Dieu via Firenze S.M.N. and Milano Centrale in around 9h 16m.
- Website
- lufthansa.com
Flights from Pisa International Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- €200–800
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 39m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €18–26
- Website
- Trenitalia
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 3h 52m
- Frequency
- 4 times a day
- Estimated price
- €35–50
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- €7–12
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Lyon
- Ave. Duration
- 10h 40m
- Frequency
- 4 times a day
- Estimated price
- €60–90
- Website
- Flixbus
Bus from Pisa to Turin
- Ave. Duration
- 9h 30m
- Frequency
- 4 times a week
- Estimated price
- €45–75
- Website
- Flixbus
Want to know more about travelling around France
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Booking & Getting There
Pisa to Lyon bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Lyon train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Lyon is 625 km. It takes approximately 6h 29m to drive from Pisa to Lyon.
Book your Pisa to Lyon train tickets online with Omio.
Book your Pisa to Lyon bus tickets online with Omio and FlixBus.
There are 3925+ hotels available in Lyon.





