There are 8 ways to get from Pisa to Mainz by train, plane, train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Frankfurt
best- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane FLR - FRA
5h 54m€135–336Fly Pisa International Airport to Cologne Bonn Airport, train
cheapest- Fly from Pisa International Airport (PSA) to Cologne Bonn Airport (CGN)plane PSA - CGN
- Take the train from Siegburg/Bonn to Frankfurt(M) Flughafen Fernbftrain
4h 3m€85–283Train via Basel
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 12 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain S5 / ...
13h 11m€166–383Bus
- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Wiesbaden Gartenfeldstraße P+Rbus
18h 11m€142–207Drive 941.3 km
- Drive from Pisa to Mainzcar 941.3 km
9h 3m€153–221Train, train to Bologna Guglielmo Marconi Airport, fly to Frankfurt
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane BLQ - FRA
6h 23m€117–364Train
- Take the train from Pisa Centrale to Milano Centraletrain Ic
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
13h 53m€165–305Bus via Milan
- Take the bus from Pisa to Milanbus FlixBus 507
- Take the bus from Milan to Mainz central train stationbus FlixBus 476
20h€101–153
Pisa to Mainz by train
Comparing Your Travel Options
The cheapest way to get from Pisa to Mainz is to bus via Milan which costs €100 - €160 and takes 20h.
The fastest way to get from Pisa to Mainz is to fly and train which takes 4h 3m and costs €80 - €290.
No, there is no direct bus from Pisa to Mainz. However, there are services departing from Pisa and arriving at Wiesbaden-Mainz-Kastel Bahnhof via Florence Villa Constanza Bus Station and Wiesbaden Hauptbahnhof. The journey, including transfers, takes approximately 18h 11m.
No, there is no direct train from Pisa to Mainz. However, there are services departing from Pisa Centrale and arriving at Mainz, Hauptbahnhof via Firenze S.M.N., Milano Centrale, Basel SBB and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 13h 11m.
The distance between Pisa and Mainz is 832 km. The road distance is 941.3 km.
The best way to get from Pisa to Mainz without a car is to train via Basel which takes 13h 11m and costs €160 - €390.
It takes approximately 5h 54m to get from Pisa to Mainz, including transfers.
Pisa to Mainz bus services, operated by FlixBus, depart from Pisa station.
Pisa to Mainz train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Mainz is to train via Basel which takes 13h 11m and costs €160 - €390. Alternatively, you can bus, which costs €140 - €210 and takes 18h 11m.
What companies run services between Pisa, Italy and Mainz, Germany?
You can take a train from Pisa Centrale to Mainz, Hauptbahnhof via Firenze S.M.N., Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 13h 11m. Alternatively, you can take a bus from Pisa to Wiesbaden-Mainz-Kastel Bahnhof via Florence Villa Constanza Bus Station, Wiesbaden Gartenfeldstraße P+R, and Wiesbaden Hauptbahnhof in around 18h 11m.
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €110–470
Flights from Florence Peretola Airport to Frankfurt via Munich
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €150–490
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €130–420
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Munich
- Ave. Duration
- 3h 38m
- When
- Monday to Saturday
- Estimated price
- €130–430
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €150–470
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €130–420
- Website
- condor.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
- Website
- eurowings.com
Flights from Pisa International Airport to Cologne Bonn Airport
- Ave. Duration
- 1h 40m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €80–240
- Website
- swiss.com
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 25m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €70–280
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 3h 47m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 39 min
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 4h 18m
- Frequency
- Every 3 hours
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Basel Sbb
- Ave. Duration
- 4h 20m
- Frequency
- Every 3 hours
- Estimated price
- €75–130
- Website
- Trenitalia Eurocity
- 1st Class
- €90–130
- 2nd Class
- €75–110
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 19m
- Frequency
- Once daily
- Estimated price
- €55–110
- Website
- Trenitalia Eurocity
- 1st Class
- €75–110
- 2nd Class
- €55–80
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- Trenitalia Eurocity
- 1st Class
- €120–180
- 2nd Class
- €120–160
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- €40–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 51m
- Frequency
- Every 3 hours
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Siegburg/Bonn to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 51 min
- Frequency
- Every 2 hours
- Estimated price
- €24–55
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €13–55
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €12–55
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- Süwex
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Siegburg/Bonn to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 41 min
- Frequency
- Every 2 hours
- Estimated price
- €15–30
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Siegburg/Bonn to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 56 min
- Frequency
- Once a week
- Estimated price
- €25–40
- Website
- Belgian Railways
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Website
- Flixbus
Bus from Pisa to Milan
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- €35–55
- Website
- Flixbus
Bus from Milan to Mainz central train station
- Ave. Duration
- 12h 15m
- Frequency
- 5 times a week
- Estimated price
- €65–100
- Website
- Flixbus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Wiesbaden Gartenfeldstraße P+R
- Ave. Duration
- 15h 2m
- Frequency
- Once a week
- Estimated price
- €130–190
- Website
- Onebus
Want to know more about travelling around Germany
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Booking & Getting There
Pisa to Mainz bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Mainz train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Mainz is 941 km. It takes approximately 9h 3m to drive from Pisa to Mainz.
Book your Pisa to Mainz train tickets online with Omio.
Book your Pisa to Mainz bus tickets online with Omio.
There are 1245+ hotels available in Mainz.













































