There are 6 ways to get from Pisa to Santander by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Pisa International Airport (PSA) to Santander Airport (SDR)plane PSA - SDR
8h 35m€85–360Train, bus via Madrid
- Take the train from Pisa Centrale to Genova P.Za Principetrain Fb / ...
- Take the bus from Genoa to Marseillebus
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
24h 10m€243–426Bus
- Take the bus from Pisa to Nice Airportbus
- Take the bus from Nice Airport to Bilbaobus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
25h 18m€123–198Drive 1,431.8 km
- Drive from Pisa to Santandercar 1,431.8 km
14h 5m€233–336Train, bus
- Take the train from Pisa Centrale to Ventimigliatrain Ic
- Take the train from Ventimiglia to Nice Saint-Augustintrain C3
- Take the bus from Nice Airport to Bilbaobus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
25h 46m€137–228Train, bus #2
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Padovatrain Fr
- Take the bus from Padova to Estación de autobuses de Santanderbus
29h 6m€159–218
Pisa to Santander by train and bus
Comparing Your Travel Options
The cheapest way to get from Pisa to Santander is to bus which costs €120 - €200 and takes 25h 18m.
The fastest way to get from Pisa to Santander is to fly which takes 8h 35m and costs €85 - €360.
No, there is no direct bus from Pisa to Santander. However, there are services departing from Pisa and arriving at Estación de autobuses de Santander via Nice Airport and Bilbao Intermodal. The journey, including transfers, takes approximately 25h 18m.
The distance between Pisa and Santander is 1145 km. The road distance is 1431.8 km.
The best way to get from Pisa to Santander without a car is to train and bus via Madrid which takes 24h 10m and costs €240 - €430.
It takes approximately 8h 35m to fly from Pisa International Airport (PSA) to Santander Airport (SDR), including transfers and time at the airport.
Pisa to Santander bus services, operated by FlixBus, depart from Pisa station.
The best way to get from Pisa to Santander is to fly which takes 8h 35m and costs €85 - €360. Alternatively, you can bus, which costs €120 - €200 and takes 25h 18m.
There is no direct flight from Pisa International Airport Airport to Santander Airport Airport. The quickest flight takes 14h 35m and has one stopover.
Pisa to Santander bus services, operated by FlixBus, arrive at Nice Airport station.
What companies run services between Pisa, Italy and Santander, Spain?
Ryanair, Volotea, and three other airlines fly from Pisa International Airport (PSA) to Santander Airport (SDR) twice daily. Alternatively, you can take a bus from Pisa to Estación de autobuses de Santander via Nice Airport, Bilbao, and Bilbao Intermodal in around 25h 18m.
- Website
- iberia.com
Flights from Pisa International Airport to Santander Airport via Madrid
- Ave. Duration
- 13h 15m
- When
- Monday, Thursday, and Sunday
- Estimated price
- €85–360
Flights from Pisa International Airport to Santander Airport via Paris Orly
- Ave. Duration
- 13h 40m
- When
- Monday and Friday
- Estimated price
- €110–600
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Pisa Centrale to Genova P.Za Principe
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €22–40
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Padova
- Ave. Duration
- 1h 44m
- Frequency
- Hourly
- Estimated price
- €30–55
- Website
- Trenitalia Frecce
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Genoa to Marseille
- Ave. Duration
- 6h 35m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Flixbus
Bus from Pisa to Nice Airport
- Ave. Duration
- 5h 30m
- Frequency
- 5 times a week
- Estimated price
- €30–45
- Website
- Flixbus
Bus from Nice Airport to Bilbao
- Ave. Duration
- 16h 40m
- Frequency
- 3 times a week
- Estimated price
- €85–140
- Website
- Flixbus
Bus from Nice Airport to Bilbao
- Ave. Duration
- 16h 40m
- Frequency
- 3 times a week
- Estimated price
- €85–140
- Website
- Flixbus
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Yes, the driving distance between Pisa to Santander is 1432 km. It takes approximately 14h 5m to drive from Pisa to Santander.
Transavia France, Vueling Airlines, Volotea and two other airlines offer flights from Pisa International Airport Airport to Santander Airport Airport.
Book your Pisa to Santander bus tickets online with Omio.
There are 2050+ hotels available in Santander.








