There are 9 ways to get from Pisa to Sicily by plane, train, ferry, train (Trenitalia), bus, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Pisa International Airport to Palermo Airport
best- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
2h 22m€41–228Bus to Florence Peretola Airport, fly to Catania–Fontanarossa Airport
cheapest- Take the bus from Pisa International Airport to Florence Airportbus
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
4h 8m€40–205Train, ferry
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Napoli Centraletrain Fr
- Take the ferry from Naples Beverello to Port of Palermoferry
14h 12m€97–199Train
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
16h 20m€128–250Bus
- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Palermobus N597 / ...
20h 6m€120–184Fly Pisa International Airport to Catania–Fontanarossa Airport
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
1h 57m€43–200Drive, car ferry
- Drive from Pisa to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
16h 22m€102–145Car ferry
- Take the carferry from Livorno to Port of Palermocarferry
22h 11m€69–155Train, bus
- Take the train from Pisa Centrale to Firenze S.M.N.train Re / ...
- Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus
23h 3m€203–287
Pisa to Sicily by train, subway, ferry, foot, and bus
Comparing Your Travel Options
The cheapest way to get from Pisa to Sicily is to fly which costs €40 - €230 and takes 2h 22m.
The fastest way to get from Pisa to Sicily is to fly which takes 1h 57m and costs €40 - €200.
No, there is no direct bus from Pisa to Sicily. However, there are services departing from Pisa and arriving at Piazza Boiardo via Florence Villa Constanza Bus Station and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 20h 6m.
No, there is no direct ferry from Pisa to Sicily. However, there are services departing from Livorno and arriving at Port of Palermo via . The journey, including transfers, takes approximately 22h 11m.
No, there is no direct train from Pisa to Sicily. However, there are services departing from Pisa Centrale and arriving at Palermo Notarbartolo via Firenze S.M.N., Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 16h 20m.
The distance between Pisa and Sicily is 685 km.
The best way to get from Pisa to Sicily without a car is to train and ferry which takes 14h 12m and costs €95 - €200.
It takes approximately 2h 22m to get from Pisa to Sicily, including transfers.
Pisa to Sicily bus services, operated by FlixBus, depart from Pisa station.
Pisa to Sicily train services, operated by Trenitalia, depart from Pisa Centrale station.
What companies run services between Pisa, Italy and Sicily, Italy?
Ulendo Airlink and Ryanair fly from Pisa International Airport (PSA) to Palermo Airport (PMO) 4 times a day. Alternatively, you can take a train from Pisa Centrale to Palermo Notarbartolo via Firenze S.M.N., Roma Termini, and Palermo Centrale in around 16h 20m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
Flights from Pisa International Airport to Palermo Airport via Bari
- Ave. Duration
- 3h 20m
- When
- Sunday
- Estimated price
- €35–200
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €35–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 4h 5m
- When
- Monday
- Estimated price
- €35–190
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- €90–190
- Website
- flyulendo.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €16–65
- Website
- volotea.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €16–110
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €90–190
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €35–190
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 4h 31m
- Frequency
- 4 times a day
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Napoli Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- €65–110
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 30 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Napoli Centrale
- Ave. Duration
- 3h 37m
- Frequency
- 5 times a day
- Estimated price
- €55–95
- Website
- Italo Treno
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 47m
- Frequency
- 5 times a day
- Estimated price
- €30–50
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- Flixbus
- Phone
- +352 50 55 62 63 10
- [email protected]
- Website
- Flibco
Bus from Pisa International Airport to Florence Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €12–22
- Website
- Flibco
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairoli
- Ave. Duration
- 19h 40m
- Frequency
- Twice a week
- Estimated price
- €190–270
- Website
- Onebus
- Phone
- +39.081.496.444
- [email protected]
- Website
- Grimaldi Lines
Ferry from Naples Beverello to Port of Palermo
- Ave. Duration
- 7h 30m
- Frequency
- 6 times a week
- Estimated price
- €30–70
- Website
- Grimaldi Lines
Car ferry from Livorno to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- 6 times a week
- Estimated price
- €65–150
- Website
- Grimaldi Lines
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Travelling by boat in Italy
Read the travel guide
Booking & Getting There
The best way to get from Pisa to Sicily is to fly which takes 2h 22m and costs €40 - €230. Alternatively, you can train, which costs €120 - €250 and takes 16h 20m, you could also bus, which costs €120 - €190 and takes 20h 6m.
Pisa to Sicily bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Sicily train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Pisa to Sicily train tickets online with Omio.
There are 6119+ hotels available in Sicily.

































