There are 10 ways to get from Pisa to Sicily by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
2h 13m€31–183Train, ferry
- Take the train from Pisa Centrale to Roma Tiburtinatrain Fa
- Take the train from Roma Tiburtina to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
13h 37mDrive, car ferry
- Drive from Pisa to Civitavecchia Portcar
- Take the car ferry from Civitavecchia Port to Palermo Portocarferry
16h 22m€95–148Bus
- Take the bus from Pisa Airport to Florence Villa Constanza Bus Stationbus BlaBlaCar Bus
- Take the bus from Florence Villa Constanza Bus Station to Palermobus N597 / ...
19h 33m€109–194Fly to Catania–Fontanarossa Airport
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
1h 57m€43–151Fly to Vincenzo Magliocco Airport
- Fly from Pisa International Airport (PSA) to Vincenzo Magliocco Airport (CIY)plane PSA - CIY
1h 55m€96–256Fly to Trapani Airport
- Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane PSA - TPS
2h 55m€40–129Train (Trenitalia)
- Take the train from Pisa Centrale to Roma Tiburtinatrain Fa
- Take the train from Roma Termini to Palermo Centraletrain Ic
15h 34m€142–290Car ferry
- Take the car ferry from Livorno to Port of Palermocarferry
22h 13m€64–115Bus via Palermo Piazza Cairoli
- Take the bus from Pisa Airport to Florence Villa Constanza Bus Stationbus BlaBlaCar Bus
- Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus
22h 18m
Pisa International Airport (PSA) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Pisa to Sicily is to fly which costs €40 - €130 and takes 2h 55m.
The fastest way to get from Pisa to Sicily is to fly which takes 1h 55m and costs €95 - €260.
No, there is no direct bus from Pisa to Sicily. However, there are services departing from Pisa Airport and arriving at Piazza Boiardo via Florence Villa Constanza Bus Station and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 19h 33m.
No, there is no direct ferry from Pisa to Sicily. However, there are services departing from Livorno and arriving at Port of Palermo via . The journey, including transfers, takes approximately 22h 13m.
No, there is no direct train from Pisa to Sicily. However, there are services departing from Pisa Centrale and arriving at Palermo Notarbartolo via Roma Tiburtina, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 15h 34m.
The distance between Pisa and Sicily is 685 km.
The best way to get from Pisa to Sicily without a car is to train and ferry which takes 13h 37m and costs .
It takes approximately 2h 13m to get from Pisa to Sicily, including transfers.
Pisa to Sicily bus services, operated by BlaBlaCar Bus, depart from Pisa Airport station.
Pisa to Sicily train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
What companies run services between Pisa, Italy and Sicily, Italy?
Ryanair flies from Pisa International Airport (PSA) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a bus from Pisa Airport to Piazza Boiardo via Florence Villa Constanza Bus Station, Palermo, and Stazione Centrale Pensilina Esterna in around 19h 33m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €27–170
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €35–130
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday
- Estimated price
- €35–130
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €35–130
Flights from Pisa International Airport to Trapani Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €35–130
- Website
- aeroitalia.com
Flights from Pisa International Airport to Vincenzo Magliocco Airport
- Ave. Duration
- 1h 40m
- When
- Thursday and Sunday
- Estimated price
- €55–700
- Website
- flexflight.dk
Flights from Pisa International Airport to Vincenzo Magliocco Airport
- Ave. Duration
- 1h 40m
- When
- Thursday and Sunday
- Estimated price
- €55–700
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Roma Tiburtina
- Ave. Duration
- 2h 9m
- Frequency
- 5 times a day
- Estimated price
- €50–100
- Schedules at
- trenitalia.com
Train from Roma Tiburtina to Napoli Afragola
- Ave. Duration
- 1h 19m
- Frequency
- Every 2 hours
- Estimated price
- €30–65
- Schedules at
- trenitalia.com
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- €60–130
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Roma Tiburtina
- Ave. Duration
- 2h 9m
- Frequency
- 5 times a day
- Estimated price
- €50–100
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Tiburtina to Napoli Afragola
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €27–55
- Website
- https://www.italotreno.it/en
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 4h 11m
- Frequency
- Twice daily
- Estimated price
- €50–110
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- €23–50
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Twice daily
- Estimated price
- €90–190
- Website
- https://www.trenitalia.com/en.html
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Pisa Airport to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €6–12
- Website
- https://www.blablacar.co.uk/bus
Bus from Pisa Airport to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €6–12
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €100–180
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairoli
- Ave. Duration
- 19h 40m
- Frequency
- Twice a week
- Website
- https://onebus.it/
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 010 209 4591
- [email protected]
- Website
- gnv.it
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €55–90
- Website
- https://www.gnv.it/en
- Phone
- +39.081.496.444
- [email protected]
- Website
- grimaldi-lines.com
Car ferry from Livorno to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- 6 times a week
- Estimated price
- €60–110
- Website
- https://www.grimaldi-lines.com/en/
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Travelling by boat in Italy
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
More Questions & Answers
The best way to get from Pisa to Sicily is to fly which takes 2h 13m and costs €30 - €190. Alternatively, you can bus, which costs €100 - €200 and takes 19h 33m, you could also train, which costs €140 - €290 and takes 15h 34m.
Pisa to Sicily bus services, operated by BlaBlaCar Bus, arrive at Florence Villa Constanza Bus Station.
Pisa to Sicily train services, operated by Trenitalia Frecce, arrive at Roma Tiburtina station.
Book your Pisa to Sicily train tickets online with Omio.
There are 6390+ hotels available in Sicily.


































