There are 11 ways to get from Pisa to Sicily by plane, bus, train, ferry or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Recommended option
Fly Pisa to Catania • 1h 57m
Cheapest option
Fly Pisa to Palermo • 2h 19m
9 alternative options
Fly Pisa to Comiso • 1h 50m
Fly Pisa to Trapani • 2h 55m
Bus to Florence, fly to Catania • 4h 7m
Bus to Florence, fly to Palermo • 4h 29m
Train, ferry • 14h 39m
Train • 16h 21m
Car ferry • 19h 51m
Train, bus • 20h 32m
Bus • 21h 41m
Pisa to Sicily by train, ferry and walk
Questions & Answers
The cheapest way to get from Pisa to Sicily is to car ferry which costs €40 - €70 and takes 19h 51m.
The fastest way to get from Pisa to Sicily is to fly which takes 1h 50m and costs €45 - €950.
No, there is no direct bus from Pisa to Sicily. However, there are services departing from Pisa International Airport and arriving at Piazza Boiardo via T2 Guidoni, Florence and Stazione Centrale - Pensilina Esterna. The journey, including transfers, takes approximately 21h 41m.
No, there is no direct train from Pisa to Sicily. However, there are services departing from Pisa Centrale and arriving at Palermo Notarbartolo via Firenze S.M.N., Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 16h 21m.
The distance between Pisa and Sicily is 802 km.
The best way to get from Pisa to Sicily without a car is to train and ferry which takes 14h 39m and costs €80 - €230.
It takes approximately 1h 57m to get from Pisa to Sicily, including transfers.
Pisa to Sicily bus services, operated by Flibco, depart from Pisa International Airport station.
Pisa to Sicily train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Sicily is to fly which takes 1h 57m and costs €29 - €270. Alternatively, you can train, which costs €70 - €250 and takes 16h 21m, you could also bus, which costs €70 - €100 and takes 21h 41m.
- Distance: 801.6 km
- Duration: 1h 57m
What companies run services between Pisa, Italy and Sicily, Italy?
Ryanair flies from Pisa to Catania twice daily. Alternatively, you can take a train from Pisa to Palermo via Firenze S.M.N., Roma Termini, and Palermo Centrale in around 16h 21m.
- Website
- ryanair.com
Flights from Pisa to Catania
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €28 - €380
Flights from Pisa to Palermo
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €21 - €320
Flights from Pisa to Trapani
- Ave. Duration
- 1h 25m
- When
- Thursday, Friday, Saturday and Sunday
- Estimated price
- €35 - €330
- Website
- alitalia.com
Flights from Florence to Catania via Rome
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €75 - €320
Flights from Florence to Palermo via Rome
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- €80 - €230
- Website
- aeroitalia.com
Flights from Pisa to Comiso
- Ave. Duration
- 1h 35m
- When
- Tuesday and Thursday
- Estimated price
- €110 - €410
- Website
- flexflight.dk
Flights from Pisa to Comiso
- Ave. Duration
- 1h 35m
- When
- Tuesday and Thursday
- Estimated price
- €110 - €410
- Website
- volotea.com
Flights from Florence to Catania
- Ave. Duration
- 1h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- €35 - €310
Flights from Florence to Palermo
- Ave. Duration
- 1h 20m
- When
- Monday, Wednesday and Friday
- Estimated price
- €30 - €220
- Website
- vueling.com
Flights from Florence to Catania
- Ave. Duration
- 1h 40m
- When
- Tuesday, Thursday, Friday, Saturday and Sunday
- Estimated price
- €50 - €600
Flights from Florence to Palermo
- Ave. Duration
- 1h 25m
- When
- Wednesday and Saturday
- Estimated price
- €45 - €700
The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.
Contact Details
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €6 - €12
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €10 - €12
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- €17 - €30
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €27 - €30
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 46m
- Frequency
- Every 4 hours
- Estimated price
- €20 - €35
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €32 - €35
Frequently asked questions
Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.
Contact Details
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Napoli Afragola
- Ave. Duration
- 2h 42m
- Frequency
- Hourly
- Estimated price
- €35 - €110
- Website
- https://www.trenitalia.com/en/frecce.html
- Super Economy
- €35 - €50
- Base Standard
- €60 - €85
- Base Premium
- €75 - €110
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 3h 46m
- Frequency
- Every 4 hours
- Estimated price
- €26 - €70
- Website
- https://www.trenitalia.com/en/frecce.html
- Super Economy
- €26 - €40
- Base Standard
- €40 - €55
- Base Premium
- €45 - €70
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €21 - €75
- Website
- https://www.trenitalia.com/en/frecce.html
- Super Economy
- €21 - €29
- Base Standard
- €40 - €55
- Base Premium
- €50 - €75
Private train company Italotreno operates high-speed trains in Italy on the same tracks as Trenitalia. The routes service 21 stations across the country, including popular routes Milan-Florence, Rome-Venice and Bologna-Naples. Choose from four classes of service, all with free Wi-Fi: Smart, Comfort, Prima and Club Executive. Italo also operates Italobus – an integrated train-bus service that takes passengers from the main train stations to other Italian cities.
Contact Details
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Stazione Santa Maria Novella to Napoli Afragola
- Ave. Duration
- 2h 44m
- Frequency
- Every 3 hours
- Estimated price
- €65 - €85
- Website
- https://www.italotreno.it/en
- Smart Economy
- €65 - €85
- Smart Flex
- €65 - €85
Train from Napoli Afragola to Villa San Giovanni
- Ave. Duration
- 4h 22m
- Frequency
- Once daily
- Estimated price
- €40 - €55
- Website
- https://www.italotreno.it/en
- Smart Economy
- €40 - €55
- Smart Flex
- €40 - €55
Train from Stazione Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 37m
- Frequency
- Hourly
- Estimated price
- €45 - €60
- Website
- https://www.italotreno.it/en
- Smart Economy
- €45 - €60
- Smart Flex
- €45 - €60
Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).
Contact Details
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- €14 - €20
- Website
- https://www.trenitalia.com/
- 2nd Class
- €14 - €20
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 35m
- Frequency
- 6 times a week
- Estimated price
- €17 - €23
- Website
- https://www.trenitalia.com/
- 2nd Class
- €17 - €23
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 38m
- Frequency
- Once daily
- Estimated price
- €50 - €70
- Website
- https://www.trenitalia.com/
- 2nd Class
- €50 - €70
- Phone
- +43 51717
- Website
- nightjet.com
Train from Stazione Santa Maria Novella to Roma Termini
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a week
- Estimated price
- €35 - €160
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €130 - €160
- Seating Carriage
- €35 - €50
- Couchette Carriage
- €85 - €110
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- Phone
- +352 26 58 57 1
- info@flibco.com
- Website
- flibco.com
Bus from Pisa International Airport to Florence Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €13 - €18
- Website
- https://www.flibco.com/en
One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.de
Bus from Florence to Palermo
- Ave. Duration
- 17h 10m
- Frequency
- Once daily
- Estimated price
- €95 - €140
- Website
- https://www.flixbus.co.uk
Frequently asked questions
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Palermo Terminal Bus
- Ave. Duration
- 18h 10m
- Frequency
- 5 times a week
- Estimated price
- €40 - €60
- Website
- https://www.itabus.it/en/home
- Phone
- 48/796 473 308
- biuro@autokarpolska.com.pl
- Website
- autokarpolska.com.pl
Bus from Florence to Palermo
- Ave. Duration
- 18h 37m
- Frequency
- Once a week
- Estimated price
- €55 - €80
- Schedules at
- autokarpolska.com.pl
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Villa San Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2 - €3
- Schedules at
- blujetlines.it
The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.
Contact Details
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
Frequently asked questions
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Car ferry from Livorno to Palermo
- Ave. Duration
- 19h 30m
- Frequency
- 6 times a week
- Estimated price
- €40 - €60
- Website
- https://www.grimaldi-lines.com/en/
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Pisa to Sicily bus services, operated by Autokar Polska, arrive at Palermo station.
Pisa to Sicily train services, operated by Trenitalia Intercity, arrive at Palermo Centrale station.
Book your Pisa to Sicily train tickets online with Omio.
There are 246+ hotels available in Sicily. Prices start at €29 per night.