There are 10 ways to get from Pisa to Sicily by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
2h 13m€38–228Train, ferry
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
14h 19mDrive, car ferry
- Drive from Pisa to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
16h 22m€101–149Bus
- Take the bus from Pisa to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Palermobus N597 / ...
20h 6m€104–174Fly to Catania–Fontanarossa Airport
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
1h 57m€42–190Fly to Vincenzo Magliocco Airport
- Fly from Pisa International Airport (PSA) to Vincenzo Magliocco Airport (CIY)plane PSA - CIY
1h 55m€104–378Fly to Trapani Airport
- Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane PSA - TPS
2h 55m€40–227Train (Trenitalia)
- Take the train from Pisa Centrale to Roma Terminitrain Fb / ...
- Take the train from Roma Termini to Palermo Centraletrain Ic
15h 54m€132–298Car ferry
- Take the carferry from Livorno to Port of Palermocarferry
22h 11m€79–135Train, bus
- Take the train from Pisa Centrale to Firenze S.M.N.train Re / ...
- Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus
23h 3m€204–289
Pisa International Airport (PSA) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Pisa to Sicily is to fly which costs €40 - €230 and takes 2h 55m.
The fastest way to get from Pisa to Sicily is to fly which takes 1h 55m and costs €100 - €380.
No, there is no direct bus from Pisa to Sicily. However, there are services departing from Pisa and arriving at Piazza Boiardo via Florence Villa Constanza Bus Station and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 20h 6m.
No, there is no direct ferry from Pisa to Sicily. However, there are services departing from Livorno and arriving at Port of Palermo via . The journey, including transfers, takes approximately 22h 11m.
No, there is no direct train from Pisa to Sicily. However, there are services departing from Pisa Centrale and arriving at Palermo Notarbartolo via Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 15h 54m.
The distance between Pisa and Sicily is 685 km.
The best way to get from Pisa to Sicily without a car is to train and ferry which takes 14h 19m and costs .
It takes approximately 2h 13m to get from Pisa to Sicily, including transfers.
Pisa to Sicily bus services, operated by FlixBus, depart from Pisa station.
Pisa to Sicily train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
What companies run services between Pisa, Italy and Sicily, Italy?
Ryanair flies from Pisa International Airport (PSA) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a bus from Pisa to Piazza Boiardo via Florence Villa Constanza Bus Station, Palermo, and Stazione Centrale Pensilina Esterna in around 20h 6m.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–210
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €30–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday
- Estimated price
- €30–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €30–190
Flights from Pisa International Airport to Trapani Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €35–220
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- €9–16
- Website
- Trenitalia
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- Trenitalia
Train from Pisa Centrale to Roma Termini
- Ave. Duration
- 4h 5m
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- €9–16
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Pisa to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €7–12
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €95–160
- Website
- Flixbus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
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More Questions & Answers
The best way to get from Pisa to Sicily is to fly which takes 2h 13m and costs €35 - €230. Alternatively, you can bus, which costs €100 - €180 and takes 20h 6m, you could also train, which costs €130 - €300 and takes 15h 54m.
Pisa to Sicily bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Pisa to Sicily train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
Book your Pisa to Sicily train tickets online with Omio.
There are 6308+ hotels available in Sicily.





