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How to get fromPittsburgh Airport (PIT) to Knoxvilleby plane, train, bus, rideshare, car, bus (Greyhound), or bus (Flixbus)

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There are 6 ways to get from Pittsburgh Airport (PIT) to Knoxville by plane, train, bus, rideshare, car, bus (Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS)plane plane PIT - TYS
    3h 57m
    $202–890

  2. Drive 495.7 mi

    cheapest
    1. Drive from Pittsburgh Airport (PIT) to Knoxvillecar car 495.7 mi
    8h 16m
    $91–131

  3. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Pennsylvanian
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    24h 27m
    $271–483

  4. Airport Transfer

    1. Take the rideshare from Pittsburgh-PIT to Knoxvillerideshare rideshare 495.7 mi
    8h 16m

  5. Bus via Farragut

    1. Take the bus from Pittsburgh Intermodal Station to Port Authority Bus Terminalbus bus Greyhound US0421 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    25h 3m
    $250–379

  6. Bus

    1. Take the bus from Pittsburgh Intermodal Station to New York City Chinatownbus bus FlixBus N2640
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    28h 16m
    $169–229

Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS) flights

Calendar125Weekly Planes
Duration4h 29mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh Airport (PIT) to Knoxville.ExpandLaunch map view
  • Distance: 395 mi
  • Duration: 3h 57m

What companies run services between Pittsburgh Airport (PIT), USA and Knoxville, TN, USA?

Delta, Southwest Airlines, and two other airlines fly from Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS) hourly. Alternatively, you can take a bus from Pittsburgh International Airport to Knoxville via Seventh Ave + William Penn Pl, Pittsburgh Intermodal Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 25h 3m.

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