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How to get fromPittsburgh, Pa to Syracuseby train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus (Flixbus), or bus

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There are 7 ways to get from Pittsburgh, Pa to Syracuse by train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus (Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train Floridian
    2. Take the train from Cleveland Amtrak to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    9h 32m
    $142–309

  2. Bus via Erie

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Eriebus bus
    2. Take the bus from Erie, PA to Buffalo, NYbus bus
    3. Take the bus from Buffalo to Syracusebus bus 325
    9h 57m
    $58–115

  3. Drive 332.4 mi

    1. Drive from Pittsburgh, Pa to Syracusecar car 332.4 mi
    7h 17m
    $61–88

  4. Fly to Syracuse Hancock International Airport

    1. Fly from Pittsburgh International Airport (PIT) to Syracuse Hancock International Airport (SYR)plane plane PIT - SYR
    7h 34m
    $366–988

  5. Bus

    1. Take the bus from Pittsburgh to Buffalobus bus Fab510
    2. Take the bus from Buffalo to Syracusebus bus Adt N809 / ...
    11h 52m
    $131–242

  6. Bus #2

    1. Take the bus from Pittsburgh to Buffalobus bus Fab510
    2. Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus bus FlixBus 2686 / ...
    12h 48m
    $136–284

  7. Fly to Ithaca Tompkins Regional Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Ithaca Tompkins Regional Airport (ITH)plane plane PIT - ITH
    2. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    9h 34m
    $76–409

Pittsburgh, Pa to Syracuse by train (Amtrak)

Calendar7Weekly Trains
Duration9h 32mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh, Pa to Syracuse.ExpandLaunch map view
  • Distance: 464.6 mi
  • Duration: 9h 32m

What companies run services between Pittsburgh, Pa, PA, USA and Syracuse, NY, USA?

You can take a train from Pittsburgh Amtrak Station to Syracuse Regional Transportation Center via Cleveland Amtrak in around 9h 32m. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Syracuse via Erie, Erie, PA, and Buffalo in around 9h 57m.

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