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How to get fromPittsburgh to Cambridgeby bus, plane, train (Amtrak), car, train, or bus (Greyhound)

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There are 7 ways to get from Pittsburgh to Cambridge by bus, plane, train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Boston Logan Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Boston Logan Airport (BOS)plane plane PIT - BOS
    4h 24m

  2. Bus via Central

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Port Authority Bus Terminalbus bus Greyhound US0421 / ...
    2. Take the bus from Port Authority Bus Terminal to South Stationbus bus New York
    14h 59m
    $101–197

  3. Bus

    1. Take the bus from Pittsburgh Greyhound to Port Authority Bus Terminalbus bus Pittsburgh
    2. Take the bus from New York, NY - W 42nd Street and 9th Avenue to Boston, MA - Dalton and Belvidere Streetbus bus New York
    12h 30m
    $116–240

  4. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Pennsylvanian
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train Acela
    13h 37m
    $217–448

  5. Drive 565.9 mi

    1. Drive from Pittsburgh to Cambridgecar car 565.9 mi
    10h 21m
    $104–150

  6. Fly Pittsburgh International Airport to Theodore Francis Green State Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Theodore Francis Green State Airport (PVD)plane plane PIT - PVD
    2. Take the train from TF Green Airport to Back Baytrain train
    6h 23m
    $146–671

  7. Train to Cleveland-Hopkins International Airport, fly to Boston Logan Airport

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Boston Logan Airport (BOS)plane plane CLE - BOS
    7h 8m
    $237–1,053

Pittsburgh to Cambridge by bus

Calendar7Weekly Buses
Duration12h 30mAverage Duration
Ticket$116Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Cambridge.ExpandLaunch map view
  • Distance: 531.3 mi
  • Duration: 4h 24m

What companies run services between Pittsburgh, PA, USA and Cambridge, MA, USA?

You can take a bus from Pittsburgh Greyhound to Boston, MA - Dalton and Belvidere Street via Port Authority Bus Terminal and New York, NY - W 42nd Street and 9th Avenue in around 12h 30m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Boston via Ny Moynihan Train Hall At Penn Station in around 13h 37m.

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