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How to get fromPittsburgh to Cape Girardeauby plane, taxi, bus (Greyhound), train, car, or bus

Find Transport to Cape Girardeau

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There are 10 ways to get from Pittsburgh to Cape Girardeau by plane, taxi, bus (Greyhound), train, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pittsburgh International Airport to Williamson County Regional Airport, taxi

    best
    1. Fly from Pittsburgh International Airport (PIT) to Williamson County Regional Airport (MWA)plane plane PIT - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    7h 58m
    $227–673

  2. Drive  640.1 mi

    cheapest
    1. Drive from Pittsburgh to Cape Girardeaucar car 640.1 mi
    11h 21m
    $117–169

  3. Bus (Greyhound)

    1. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    16h 4m
    $134–196

  4. Train, taxi

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carbondaletrain train
    3. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    17h 16m
    $534–805

  5. Fly Pittsburgh International Airport to Barkley Regional Airport, taxi

    1. Fly from Pittsburgh International Airport (PIT) to Barkley Regional Airport (PAH)plane plane PIT - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    8h 9m
    $235–668

  6. Fly Pittsburgh International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 44m
    $134–629

  7. Fly Pittsburgh International Airport to Cape Girardeau Municipal Airport

    1. Fly from Pittsburgh International Airport (PIT) to Cape Girardeau Municipal Airport (CGI)plane plane PIT - CGI
    7h 26m
    $118–525

  8. Train to Cleveland-Hopkins International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    10h 19m
    $599–1,062

  9. Fly Pittsburgh International Airport to Nashville, bus, taxi

    1. Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane plane PIT - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    10h 19m
    $618–1,257

  10. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    18h 41m
    $441–684

Pittsburgh International Airport (PIT) to Williamson County Regional Airport (MWA) flights

Calendar24Weekly Planes
Duration4h 57mAverage Duration
Ticket$96Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Cape Girardeau.ExpandLaunch map view
  • Distance: 588.3 mi
  • Duration: 7h 58m

What companies run services between Pittsburgh, PA, USA and Cape Girardeau, MO, USA?

You can take a bus from Pittsburgh Intermodal Station to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 16h 4m. Alternatively, United Airlines, Corporate Flight Management Inc, and two other airlines fly from Pittsburgh International Airport (PIT) to Cape Girardeau Municipal Airport (CGI) 3 times a day.

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