There are 3 ways to get from Pittsburgh to Cleveland Clinic by train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain Floridian
3h 55m$41–99Bus
cheapest- Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus Greyhound US0164
- Take the bus from Robert K Pfaff Transit Center - Akron to Euclid Ave & E. 100th St @ Cleveland Clbus 61
4h 50m$21–31Drive 126.4 mi
- Drive from Pittsburgh to Cleveland Cliniccar 126.4 mi
2h 20m$24–34
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Cleveland Clinic is to bus which costs $20 - $35 and takes 4h 50m.
The fastest way to get from Pittsburgh to Cleveland Clinic is to drive which takes 2h 20m and costs $23 - $35.
No, there is no direct bus from Pittsburgh station to Cleveland Clinic. However, there are services departing from Pittsburgh Intermodal Station and arriving at Euclid Ave & E. 100th St @ Cleveland Cl via Robert K Pfaff Transit Center - Akron. The journey, including transfers, takes approximately 4h 50m.
No, there is no direct train from Pittsburgh station to Cleveland Clinic station. However, there are services departing from Pittsburgh Amtrak Station and arriving at E 105Th St-Quincy Av Station via Tower City Station Track 13. The journey, including transfers, takes approximately 3h 55m.
The distance between Pittsburgh and Cleveland Clinic is 145 miles. The road distance is 127.2 miles.
The best way to get from Pittsburgh to Cleveland Clinic without a car is to train which takes 3h 55m and costs $40 - $100.
It takes approximately 3h 55m to get from Pittsburgh to Cleveland Clinic, including transfers.
Pittsburgh to Cleveland Clinic bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Cleveland Clinic train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Cleveland Clinic is to train which takes 3h 55m and costs $40 - $100. Alternatively, you can bus, which costs $20 - $35 and takes 4h 50m.
What companies run services between Pittsburgh, PA, USA and Cleveland Clinic, OH, USA?
Amtrak operates a train from Pittsburgh Amtrak Station to Cleveland Amtrak once daily. Tickets cost $35–100 and the journey takes 2h 54m. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Cleveland Clinic via Robert K Pfaff Transit Center - Akron and Euclid Ave & E. 100th St @ Cleveland Cl in around 4h 50m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $35–100
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akron
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
- Phone
- +1 330 762 0341
- Website
- Akron Metro
Bus from Robert K Pfaff Transit Center - Akron to Euclid Ave & E. 100th St @ Cleveland Cl
- Ave. Duration
- 1h 22m
- Frequency
- 4 times a day
- Estimated price
- $2
- Schedules at
- Akron Metro
Want to know more about travelling around United States
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Booking & Getting There
Pittsburgh to Cleveland Clinic bus services, operated by Greyhound USA, arrive at Robert K Pfaff Transit Center - Akron station.
Pittsburgh to Cleveland Clinic train services, operated by Amtrak, arrive at Cleveland Amtrak station.
Yes, the driving distance between Pittsburgh to Cleveland Clinic is 127 miles. It takes approximately 2h 20m to drive from Pittsburgh to Cleveland Clinic.
There are 730+ hotels available in Cleveland Clinic.