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How to get fromPittsburgh to Cleveland Clinicby bus (Greyhound), train (Amtrak), or car

Find Transport to Cleveland Clinic

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There are 4 ways to get from Pittsburgh to Cleveland Clinic by bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Pittsburgh Intermodal Station to Cleveland Bus Stationbus bus Greyhound US0164 / ...
    3h 21m
    $28–39
  2. Drive  126.4 mi

    cheapest
    1. Drive from Pittsburgh to Cleveland Cliniccar car 126.4 mi
    2h 20m
    $22–32
  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train Floridian
    3h 55m
    $79–119
  4. Bus via Akron

    1. Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus bus Greyhound US0164
    2. Take the bus from RKP Transit Center to Euclid Ave & E. 100th St @ Cleveland Clinicbus bus 61
    4h 48m
    $26–36

Pittsburgh to Cleveland Clinic by bus, foot, and subway (Greyhound)

Calendar56Weekly Services
Duration3h 21mAverage Duration
Ticket$28Cheapest Price
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Comparing Your Travel Options

What companies run services between Pittsburgh, PA, USA and Cleveland Clinic, OH, USA?

Greyhound USA operates a bus from Pittsburgh Intermodal Station to Cleveland Bus Station every 4 hours. Tickets cost $24–40 and the journey takes 2h 10m. Alternatively, Amtrak operates a train from Pittsburgh Amtrak Station to Cleveland Amtrak once daily. Tickets cost $75–120 and the journey takes 2h 54m.

Train operators
Bus operators

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