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How to get fromPittsburgh to Cleveland Clinicby train (Amtrak), bus (Greyhound), or car

Find Transport to Cleveland Clinic

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There are 3 ways to get from Pittsburgh to Cleveland Clinic by train (Amtrak), bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train Floridian
    3h 55m
    $79–119
  2. Drive  126.4 mi

    cheapest
    1. Drive from Pittsburgh to Cleveland Cliniccar car 126.4 mi
    2h 20m
    $22–32
  3. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus bus Greyhound US0164
    2. Take the bus from RKP Transit Center to Euclid Ave & E. 100th St @ Cleveland Clinicbus bus 61
    4h 48m
    $26–36

Pittsburgh to Cleveland Clinic by bus and foot

Calendar7Weekly Services
Duration4h 48mAverage Duration
Ticket$26Cheapest Price
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Comparing Your Travel Options

What companies run services between Pittsburgh, PA, USA and Cleveland Clinic, OH, USA?

Amtrak operates a train from Pittsburgh Amtrak Station to Cleveland Amtrak once daily. Tickets cost $75–120 and the journey takes 2h 54m. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Cleveland Clinic via RKP Transit Center and Euclid Ave & E. 100th St @ Cleveland Clinic in around 4h 48m.

Train operators
Bus operators

Want to know more about travelling around United States

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Need to know: Greyhound

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