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How to get fromPittsburgh to DePaul Universityby bus, plane, subway, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Flixbus)

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There are 8 ways to get from Pittsburgh to DePaul University by bus, plane, subway, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Chicago Midway International Airport, subway

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    3. Take the subway from Roosevelt to Fullertonsubway subway
    4h 35m

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus bus Greyhound US0164 / ...
    11h 13m
    $80–147

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    10h 22m
    $160–319

  4. Drive 463.8 mi

    1. Drive from Pittsburgh to DePaul Universitycar car 463.8 mi
    7h 42m
    $85–123

  5. Bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport, subway

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    3. Take the subway from Lake to Fullertonsubway subway
    4h 59m

  6. Train to Johnstown-Cambria County Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Pittsburgh Amtrak Station to Johnstown Amtrak Stationtrain train
    2. Fly from Johnstown-Cambria County Airport (JST) to Chicago O'Hare International Airport (ORD)plane plane JST - ORD
    5h 46m
    $88–358

  7. Train to Cleveland-Hopkins International Airport, fly to Chicago Midway International Airport

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane plane CLE - MDW
    7h 5m
    $112–473

  8. Bus via Chicago

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    11h 43m
    $89–146

Pittsburgh to DePaul University by train, foot, bus, and subway (Amtrak)

Calendar7Weekly Services
Duration10h 22mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to DePaul University.ExpandLaunch map view
  • Distance: 440.2 mi
  • Duration: 4h 35m

What companies run services between Pittsburgh, PA, USA and DePaul University, IL, USA?

Amtrak operates a train from Pittsburgh Amtrak Station to Chicago Union Station once daily. Tickets cost $150–320 and the journey takes 9h 46m. Alternatively, Jefferson Lines operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station 3 times a day. Tickets cost $110–160 and the journey takes 10h 20m. Two other operators also service this route.

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