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How to get fromPittsburgh to Durhamby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Find Transport to Durham

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There are 5 ways to get from Pittsburgh to Durham by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Raleigh-Durham International Airport (RDU)plane plane PIT - RDU
    5h 3m

  2. Drive  407 mi

    cheapest
    1. Drive from Pittsburgh to Durhamcar car 407 mi
    9h 19m
    $75–108

  3. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Washington Union Station to Durhambus bus FlixBus N2471 / ...
    11h 50m
    $83–144

  4. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Raleigh Union Stationtrain train Floridian
    2. Take the train from Raleigh Union Station to Durham Amtrak Stationtrain train Piedmont / ...
    15h 46m
    $340–522

  5. Train to Cleveland-Hopkins International Airport, fly

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Raleigh-Durham International Airport (RDU)plane plane CLE - RDU
    7h 48m
    $185–775

Pittsburgh to Durham by bus

Calendar29Weekly Buses
Duration11h 50mAverage Duration
Ticket$83Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Durham.ExpandLaunch map view
  • Distance: 370.9 mi
  • Duration: 5h 3m

What companies run services between Pittsburgh, PA, USA and Durham, NC, USA?

You can take a bus from Pittsburgh Intermodal Station to Durham via Washington Union Station in around 11h 50m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Durham Amtrak Station via Raleigh Union Station in around 15h 46m.

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