There are 10 ways to get from Pittsburgh to Durham by plane, train, train (Amtrak), bus, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Pittsburgh International Airport to Boston Logan Airport, train
best- Fly from Pittsburgh International Airport (PIT) to Boston Logan Airport (BOS)plane PIT - BOS
- Take the train from Woburn Amtrak Station to Durham Stationtrain
6h 50m$455–988Fly Pittsburgh International Airport to Theodore Francis Green State Airport, train
cheapest- Fly from Pittsburgh International Airport (PIT) to Theodore Francis Green State Airport (PVD)plane PIT - PVD
- Take the train from TF Green Airport to Rugglestrain
- Take the train from Boston to Durham Stationtrain
8h 54m$102–415Train (Amtrak)
- Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the train from Boston to Durham Stationtrain
16h 11m$393–626Bus, train
- Take the bus from Pittsburgh Intermodal Station to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Bostonbus
- Take the train from Boston to Durham Stationtrain
17h 6m$150–239Drive 618.5 mi
- Drive from Pittsburgh to Durhamcar 618.5 mi
11h 34m$106–153Fly Pittsburgh International Airport to Portland, train
- Fly from Pittsburgh International Airport (PIT) to Portland (PWM)plane PIT - PWM
- Take the train from Portland to Durham Stationtrain
7h 19m$118–524Train to Cleveland-Hopkins International Airport, fly to Boston Logan Airport, train
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Boston Logan Airport (BOS)plane CLE - BOS
- Take the train from Woburn Amtrak Station to Durham Stationtrain
9h 29m$235–1,123Fly Pittsburgh International Airport to Bradley International Airport, bus, train
- Fly from Pittsburgh International Airport (PIT) to Bradley International Airport (BDL)plane PIT - BDL
- Take the bus from Hartford Union Station to Bostonbus
- Take the train from Boston to Durham Stationtrain
9h 29m$111–598Fly Pittsburgh International Airport to Manchester Airport, bus, train
- Fly from Pittsburgh International Airport (PIT) to Manchester Airport (MHT)plane PIT - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
- Take the train from Boston to Durham Stationtrain
11h 19m$124–532Bus
- Take the bus from Pittsburgh Greyhound to Port Authority Bus Terminalbus
- Take the bus from New York to Bostonbus
- Take the bus from Boston to Portsmouth Bus Stopbus
17h 50m$104–178
Pittsburgh to Durham by train and subway (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Durham is to bus which costs $100 - $180 and takes 17h 50m.
The fastest way to get from Pittsburgh to Durham is to fly and train which takes 6h 50m and costs $450 - $1,000.
No, there is no direct bus from Pittsburgh to Durham. However, there are services departing from Pittsburgh Greyhound and arriving at Dover Transportation Center via New York, Boston and Hanover Station. The journey, including transfers, takes approximately 17h 50m.
No, there is no direct train from Pittsburgh station to Durham station. However, there are services departing from Pittsburgh Amtrak Station and arriving at Durham Station via Ny Moynihan Train Hall At Penn Station, Back Bay and Boston. The journey, including transfers, takes approximately 16h 11m.
The distance between Pittsburgh and Durham is 589 miles. The road distance is 622.1 miles.
The best way to get from Pittsburgh to Durham without a car is to train which takes 16h 11m and costs $390 - $650.
It takes approximately 6h 50m to get from Pittsburgh to Durham, including transfers.
Pittsburgh to Durham bus services, operated by Megabus, depart from Pittsburgh Greyhound station.
Pittsburgh to Durham train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Durham is to train which takes 16h 11m and costs $390 - $650. Alternatively, you can bus, which costs $100 - $180 and takes 17h 50m.
What companies run services between Pittsburgh, PA, USA and Durham, NH, USA?
You can take a train from Pittsburgh Amtrak Station to Durham Station via Ny Moynihan Train Hall At Penn Station, Boston, Back Bay, North Station, and Boston in around 16h 11m. Alternatively, you can take a bus from Pittsburgh Greyhound to Durham Station via Port Authority Bus Terminal, New York, Boston, Portsmouth Bus Stop, Hanover Station, Dover Transportation Center, and Dover in around 17h 50m.
- Website
- united.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 3h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Flights from Pittsburgh International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $85–500
Flights from Pittsburgh International Airport to Portland via Washington Dulles
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $90–490
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 3h 36m
- When
- Sunday, Monday, Wednesday, Thursday, Friday, and Tuesday
- Estimated price
- $60–350
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 3h 58m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Pittsburgh International Airport to Bradley International Airport via Washington Dulles
- Ave. Duration
- 3h 27m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $110–700
Flights from Pittsburgh International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $85–470
- Website
- delta.com
Flights from Pittsburgh International Airport to Boston Logan Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $80–490
Flights from Pittsburgh International Airport to Boston Logan Airport via New York JFK
- Ave. Duration
- 3h 54m
- When
- Saturday and Sunday
- Estimated price
- $85–500
Flights from Pittsburgh International Airport to Portland via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $85–480
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $90–550
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Detroit
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $100–600
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Pittsburgh International Airport to Bradley International Airport via Detroit
- Ave. Duration
- 3h 46m
- When
- Sunday
- Estimated price
- $140–800
- Website
- southwest.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 35m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $90–550
Flights from Pittsburgh International Airport to Portland via Baltimore
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–490
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 3h 35m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $60–350
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 52m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $100–550
Flights from Pittsburgh International Airport to Bradley International Airport via Baltimore
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $110–700
Flights from Pittsburgh International Airport to Manchester Airport via Baltimore
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $80–470
Flights from Pittsburgh International Airport to Manchester Airport via Chicago Midway
- Ave. Duration
- 7h 37m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
- Website
- aa.com
Flights from Pittsburgh International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 50m
- When
- Monday to Friday
- Estimated price
- $85–500
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 4h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Pittsburgh International Airport to Bradley International Airport via Reagan Washington
- Ave. Duration
- 3h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Pittsburgh International Airport to Manchester Airport via Reagan Washington
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $85–480
Flights from Pittsburgh International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $80–460
Flights from Pittsburgh International Airport to Manchester Airport via Charlotte
- Ave. Duration
- 5h 57m
- When
- Thursday, Friday, Sunday, and Monday
- Estimated price
- $120–600
- Website
- jetblue.com
Flights from Pittsburgh International Airport to Boston Logan Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $80–490
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $90–550
- Website
- flybreeze.com
Flights from Pittsburgh International Airport to Portland
- Ave. Duration
- 1h 36m
- When
- Thursday and Sunday
- Estimated price
- $180–1,100
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 1h 32m
- When
- Thursday and Sunday
- Estimated price
- $130–800
Flights from Pittsburgh International Airport to Bradley International Airport
- Ave. Duration
- 1h 28m
- When
- Monday and Friday
- Estimated price
- $60–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Woburn Amtrak Station to Durham Station
- Ave. Duration
- 1h 4m
- Frequency
- 5 times a day
- Estimated price
- $27–45
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $240–370
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Boston to Durham Station
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $30–55
- Website
- Amtrak
Train from Boston to Durham Station
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $30–55
- Website
- Amtrak
Train from Portland to Durham Station
- Ave. Duration
- 1h 7m
- Frequency
- Every 4 hours
- Estimated price
- $29–45
- Website
- Amtrak
Train from Boston to Durham Station
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $30–55
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Amtrak
Train from Woburn Amtrak Station to Durham Station
- Ave. Duration
- 1h 4m
- Frequency
- 5 times a day
- Estimated price
- $27–45
- Website
- Amtrak
Train from Boston to Durham Station
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $30–55
- Website
- Amtrak
Train from Boston to Durham Station
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $30–55
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from TF Green Airport to Ruggles
- Ave. Duration
- 1h 22m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Port Authority Bus Terminal
- Ave. Duration
- 8h 50m
- Frequency
- Every 2 hours
- Estimated price
- $80–130
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Boston
- Ave. Duration
- 5h 4m
- Frequency
- Hourly
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Hartford Union Station to Boston
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $18–28
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Estimated price
- $10–16
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Hartford Union Station to Boston
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $15–24
- Schedules at
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $9–14
- Schedules at
- Flixbus USA
- Phone
- +1-877-462-6342
- [email protected]
- Website
- Megabus
Bus from Pittsburgh Greyhound to Port Authority Bus Terminal
- Ave. Duration
- 7h 50m
- Frequency
- Hourly
- Estimated price
- $50–80
- Website
- Megabus
- Adult One-way
- $50–80
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from New York to Boston
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–75
- Website
- Peter Pan
Want to know more about travelling around United States
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Booking & Getting There
Pittsburgh to Durham bus services, operated by Megabus, arrive at Port Authority Bus Terminal station.
Pittsburgh to Durham train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Pittsburgh to Durham is 622 miles. It takes approximately 11h 34m to drive from Pittsburgh to Durham.
Book your Pittsburgh to Durham train tickets online with Omio.
Book your Pittsburgh to Durham bus tickets online with Omio.
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