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How to get fromPittsburgh to Grand Central Stationby bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Flixbus)

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There are 8 ways to get from Pittsburgh to Grand Central Station by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    4h 22m

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus bus Greyhound US0164
    10h 17m
    $70–140

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    9h 59m
    $150–320

  4. Drive 459.9 mi

    1. Drive from Pittsburgh to Grand Central Stationcar car 459.9 mi
    7h 35m
    $84–122

  5. Bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    4h 48m

  6. Train to Johnstown-Cambria County Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Pittsburgh Amtrak Station to Johnstown Amtrak Stationtrain train
    2. Fly from Johnstown-Cambria County Airport (JST) to Chicago O'Hare International Airport (ORD)plane plane JST - ORD
    5h 35m
    $86–353

  7. Train to Cleveland-Hopkins International Airport, fly to Chicago Midway International Airport

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane plane CLE - MDW
    6h 51m
    $110–479

  8. Bus via Chicago (Flixbus)

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    11h 31m
    $90–150

Pittsburgh to Grand Central Station by train and foot (Amtrak)

Calendar7Weekly Services
Duration9h 59mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Grand Central Station.ExpandLaunch map view
  • Distance: 436.4 mi
  • Duration: 4h 22m

What companies run services between Pittsburgh, PA, USA and Grand Central Station, IL, USA?

Amtrak operates a train from Pittsburgh Amtrak Station to Chicago Union Station once daily. Tickets cost $150–320 and the journey takes 9h 46m. Alternatively, Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $70–140 and the journey takes 10h 5m. Flixbus USA also services this route once daily.

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