There are 8 ways to get from Pittsburgh to Great Lakes by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Pittsburgh International Airport, fly
best- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane PIT - ORD
4h 39mBus to Morgantown Municipal Airport, fly
cheapest- Take the bus from Pittsburgh Greyhound to Westover Terminalbus
- Fly from Morgantown Municipal Airport (MGW) to Chicago O'Hare International Airport (ORD)plane MGW - ORD
7h 1m$46–306Train (Amtrak)
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain Floridian
9h 58m$120–274Bus
- Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus Greyhound US0164
10h 29m$75–120Drive 460 mi
- Drive from Pittsburgh to Chicagocar 460 mi
7h 36m$84–122Train to Johnstown-Cambria County Airport, fly
- Take the train from Pittsburgh Amtrak Station to Johnstown Amtrak Stationtrain
- Fly from Johnstown-Cambria County Airport (JST) to Chicago O'Hare International Airport (ORD)plane JST - ORD
5h 32m$80–346Bus to Akron, fly
- Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus
- Fly from Akron (CAK) to Chicago O'Hare International Airport (ORD)plane CAK - ORD
7h 9m$55–263Bus via Chicago (Flixbus)
- Take the bus from Pittsburgh Intermodal Station to Chicagobus FlixBus N2640
11h 21m$82–124
Pittsburgh to Great Lakes by train and bus (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Great Lakes is to bus which costs $70 - $120 and takes 10h 29m.
The fastest way to get from Pittsburgh to Great Lakes is to train and fly which takes 5h 32m and costs $75 - $350.
No, there is no direct bus from Pittsburgh station to Great Lakes. However, there are services departing from Pittsburgh Intermodal Station and arriving at Congress Plaza & Michigan via Jefferson & Harrison. The journey, including transfers, takes approximately 10h 29m.
No, there is no direct train from Pittsburgh station to Great Lakes station. However, there are services departing from Pittsburgh Amtrak Station and arriving at Chicago Union Station via . The journey, including transfers, takes approximately 9h 58m.
The distance between Pittsburgh and Great Lakes is 456 miles. The road distance is 462.7 miles.
The best way to get from Pittsburgh to Great Lakes without a car is to train which takes 9h 58m and costs $120 - $280.
It takes approximately 4h 39m to get from Pittsburgh to Great Lakes, including transfers.
Pittsburgh to Great Lakes bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Great Lakes train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Great Lakes is to train which takes 9h 58m and costs $120 - $280. Alternatively, you can bus, which costs $70 - $120 and takes 10h 29m.
What companies run services between Pittsburgh, PA, USA and Great Lakes, MI, USA?
Amtrak operates a train from Pittsburgh Amtrak Station to Chicago Union Station once daily. Tickets cost $110–280 and the journey takes 9h 46m. Alternatively, Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $75–120 and the journey takes 10h 5m. Flixbus USA also services this route once daily.
- Website
- united.com
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $50–330
Flights from Johnstown-Cambria County Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $45–280
Flights from Johnstown-Cambria County Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $55–310
Flights from Morgantown Municipal Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $40–270
Flights from Morgantown Municipal Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $55–310
Flights from Akron to Chicago O'Hare International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $35–230
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Johnstown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Once daily
- Estimated price
- $18–45
- Website
- Amtrak
- Phone
- +1 412-442-2000
- Website
- Pittsburgh Regional Transit
Bus from Seventh Ave + Smithfield St to Pittsburgh International Airport
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
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Booking & Getting There
Pittsburgh to Great Lakes bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Pittsburgh to Great Lakes train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Pittsburgh to Great Lakes is 463 miles. It takes approximately 7h 36m to drive from Pittsburgh to Great Lakes.
There are 64+ hotels available in Great Lakes.



