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How to get fromPittsburgh to Great Lakesby bus, plane, train, train (Amtrak), bus (Greyhound, Flixbus), or car

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There are 7 ways to get from Pittsburgh to Great Lakes by bus, plane, train, train (Amtrak), bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Chicago Midway International Airport, train

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    3. Take the train from Chicago OTC to Great Lakestrain train
    6h 13m
  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus bus Greyhound US0164
    13h 42m
    $80–147
  3. Train

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago OTC to Great Lakestrain train Up-N
    11h 40m
    $161–323
  4. Drive 495.4 mi

    1. Drive from Pittsburgh to Great Lakescar car 495.4 mi
    8h 20m
    $91–131
  5. Fly Pittsburgh International Airport to Chicago O'Hare International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    2. Take the train from Clybourn to Great Lakestrain train
    6h 34m
    $393–1,144
  6. Train to Johnstown-Cambria County Airport, fly to Chicago O'Hare International Airport, train

    1. Take the train from Pittsburgh Amtrak Station to Johnstown Amtrak Stationtrain train
    2. Fly from Johnstown-Cambria County Airport (JST) to Chicago O'Hare International Airport (ORD)plane plane JST - ORD
    3. Take the train from Clybourn to Great Lakestrain train
    7h 21m
    $90–360
  7. Bus, train

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    2. Take the train from Chicago OTC to Great Lakestrain train Up-N
    14h 9m
    $94–151

Pittsburgh to Great Lakes by train, foot, and bus

Calendar7Weekly Services
Duration11h 40mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Great Lakes, IL, USA?

You can take a train from Pittsburgh Amtrak Station to Great Lakes via Chicago Union Station, Washington & Jefferson, Washington & Canal, and Chicago OTC in around 11h 40m. Alternatively, Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $70–140 and the journey takes 10h 5m. Flixbus USA also services this route once daily.

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