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How to get fromPittsburgh to Great Smoky Mountainsby plane, car, bus, or train

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There are 9 ways to get from Pittsburgh to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS)plane plane PIT - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 44m
    $142–734

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane plane PIT - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    7h 47m
    $82–407

  3. Bus, drive

    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Take the bus from Morgantown to Charlestonbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from New Leicester Hwy at Walgreens to Great Smoky Mountainscar car
    19h 2m
    $89–220

  4. Train, bus, drive

    1. Take the train from Pittsburgh Amtrak Station to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    23h 20m
    $256–515

  5. Drive 511.1 mi

    1. Drive from Pittsburgh to Great Smoky Mountainscar car 511.1 mi
    9h 22m
    $94–135

  6. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    6h 48m
    $123–600

  7. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane PIT - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    8h 1m
    $132–584

  8. Fly to Nashville, drive

    1. Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane plane PIT - BNA
    2. Drive from Nashville-Airport-BNA to Great Smoky Mountainscar car
    8h 20m
    $560–1,063

  9. Bus, drive via New York

    1. Take the bus from Pittsburgh Intermodal Station to New York City Chinatownbus bus
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    3. Drive from Knoxville, TN to Great Smoky Mountainscar car
    24h 29m
    $180–248

Pittsburgh International Airport (PIT) to Mcghee Tyson Airport (TYS) flights

Calendar125Weekly Planes
Duration4h 29mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 466.8 mi
  • Duration: 7h 44m

What companies run services between Pittsburgh, PA, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Pittsburgh to Great Smoky Mountains. However, you can take the bus to Pittsburgh International Airport, walk to Pittsburgh-Airport-PIT airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Pittsburgh Greyhound to Great Smoky Mountains via Westover Terminal, Morgantown, Charleston Bus Station, Winston Salem(Trans Center), Asheville, NC, ART Station, and New Leicester Hwy at Walgreens in around 19h 2m.

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