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How to get fromPittsburgh to Greenvilleby bus, plane, train, bus (Greyhound), car, or taxi

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There are 5 ways to get from Pittsburgh to Greenville by bus, plane, train, bus (Greyhound), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    3h 57m

  2. Drive 518.6 mi

    cheapest
    1. Drive from Pittsburgh to Greenvillecar car 518.6 mi
    9h 27m
    $95–137

  3. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    22h 43m
    $300–667

  4. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus
    2. Take the bus from Columbus to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    27h 20m
    $191–414

  5. Fly to Asheville Regional Airport, taxi

    1. Fly from Pittsburgh International Airport (PIT) to Asheville Regional Airport (AVL)plane plane PIT - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    6h 42m
    $208–555

Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP) flights

Calendar58Weekly Planes
Duration3h 30mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Greenville.ExpandLaunch map view
  • Distance: 439.4 mi
  • Duration: 3h 57m

What companies run services between Pittsburgh, PA, USA and Greenville, SC, USA?

You can take a bus from Pittsburgh Intermodal Station to Greenville via Columbus, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 27h 20m.

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