There are 9 ways to get from Pittsburgh to Hopkinton by plane, train, bus, train (Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Pittsburgh International Airport to Boston Logan Airport, train
best- Fly from Pittsburgh International Airport (PIT) to Boston Logan Airport (BOS)plane PIT - BOS
- Take the train from Back Bay to Southboroughtrain
7h 17m$434–970Fly Pittsburgh International Airport to Theodore Francis Green State Airport, train
cheapest- Fly from Pittsburgh International Airport (PIT) to Theodore Francis Green State Airport (PVD)plane PIT - PVD
- Take the train from TF Green Airport to Back Baytrain
- Take the train from Back Bay to Southboroughtrain
9h 13m$73–368Bus via New York
- Take the bus from Pittsburgh Greyhound to Port Authority Bus Terminalbus Pittsburgh
- Take the bus from New York to Worcesterbus Ppb 5613 / ...
14h 20m$91–151Train
- Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the train from Back Bay to Southboroughtrain
16h 31m$169–407Drive 545 mi
- Drive from Pittsburgh to Hopkintoncar 545 mi
9h 56m$100–144Fly Pittsburgh International Airport to Worcester Regional Airport
- Fly from Pittsburgh International Airport (PIT) to Worcester Regional Airport (ORH)plane PIT - ORH
9h 44m$81–449Bus to Pittsburgh International Airport, fly to Bradley International Airport, bus, train
- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Bradley International Airport (BDL)plane PIT - BDL
- Take the bus from Hartford to Worcesterbus
- Take the train from Worcester to Southboroughtrain
8h 59mTrain to Cleveland-Hopkins International Airport, fly to Boston Logan Airport, train
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Boston Logan Airport (BOS)plane CLE - BOS
- Take the train from Back Bay to Southboroughtrain
10h 4m$192–1,055Bus (Greyhound)
- Take the bus from Pittsburgh Intermodal Station to Port Authority Bus Terminalbus Greyhound US0421 / ...
- Take the bus from Port Authority Bus Terminal to Worcester Union Stationbus Greyhound US0240 / ...
16h 35m$102–165
Pittsburgh to Hopkinton by bus and train
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Hopkinton is to bus via New York which costs $90 - $160 and takes 14h 20m.
The fastest way to get from Pittsburgh to Hopkinton is to fly and train which takes 7h 17m and costs $430 - $1,000.
No, there is no direct bus from Pittsburgh to Hopkinton. However, there are services departing from Pittsburgh Greyhound and arriving at Hopkinton Center via New York and Southborough MBTA Station. The journey, including transfers, takes approximately 14h 20m.
No, there is no direct train from Pittsburgh station to Hopkinton. However, there are services departing from Pittsburgh Amtrak Station and arriving at Southborough via Ny Moynihan Train Hall At Penn Station and Back Bay. The journey, including transfers, takes approximately 16h 31m.
The distance between Pittsburgh and Hopkinton is 564 miles. The road distance is 548.2 miles.
The best way to get from Pittsburgh to Hopkinton without a car is to bus via New York which takes 14h 20m and costs $90 - $160.
It takes approximately 7h 17m to get from Pittsburgh to Hopkinton, including transfers.
Pittsburgh to Hopkinton bus services, operated by Megabus, depart from Pittsburgh Greyhound station.
Pittsburgh to Hopkinton train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Hopkinton is to bus via New York which takes 14h 20m and costs $90 - $160. Alternatively, you can train, which costs $160 - $410 and takes 16h 31m, you could also fly, which costs $80 - $450 and takes 9h 44m.
What companies run services between Pittsburgh, PA, USA and Hopkinton, MA, USA?
You can take a bus from Pittsburgh Greyhound to Hopkinton Center via Port Authority Bus Terminal, New York, Worcester, Worcester, Southborough, and Southborough MBTA Station in around 14h 20m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Hopkinton Center via Ny Moynihan Train Hall At Penn Station, Boston, Back Bay, Southborough, and Southborough MBTA Station in around 16h 31m.
- Website
- united.com
Flights from Pittsburgh International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $85–490
Flights from Pittsburgh International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $75–470
Flights from Pittsburgh International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $60–350
Flights from Pittsburgh International Airport to Bradley International Airport via Washington Dulles
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $95–600
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $85–490
Flights from Cleveland-Hopkins International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $95–550
Train from Back Bay to Southborough
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Back Bay to Southborough
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from TF Green Airport to Back Bay
- Ave. Duration
- 1h 23m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from Back Bay to Southborough
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Worcester to Southborough
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from Back Bay to Southborough
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
- Phone
- +1-877-462-6342
- [email protected]
- Website
- Megabus
Bus from Pittsburgh Greyhound to Port Authority Bus Terminal
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Megabus
- Adult One-way
- $50–80
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Booking & Getting There
Pittsburgh to Hopkinton bus services, operated by Megabus, arrive at Port Authority Bus Terminal station.
Pittsburgh to Hopkinton train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Pittsburgh to Hopkinton is 548 miles. It takes approximately 9h 56m to drive from Pittsburgh to Hopkinton.
There are 122+ hotels available in Hopkinton.







