There are 6 ways to get from Pittsburgh to Indianapolis, IN by bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Indianapolis (Flixbus)
best- Take the bus from Pittsburgh Intermodal Station to Indianapolisbus FlixBus N2642 / ...
7h 31m$50–85Train (Amtrak)
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain Floridian
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
15h 40m$183–408Drive 358.1 mi
- Drive from Pittsburgh to Indianapolis, INcar 358.1 mi
6h 11m$66–95Fly to Indianapolis
- Fly from Pittsburgh International Airport (PIT) to Indianapolis (IND)plane PIT - IND
6h 54m$457–972Bus (Greyhound)
- Take the bus from Pittsburgh Intermodal Station to Indianapolis Union Stationbus Greyhound US0421
7h 50m$50–100Fly to Louisville International Airport, bus
- Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane PIT - SDF
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
8h 41m$137–692
Pittsburgh to Indianapolis, IN by bus and foot (Flixbus)
Questions & Answers
The cheapest way to get from Pittsburgh to Indianapolis, IN is to bus via Indianapolis which costs $50 - $85 and takes 7h 31m.
The fastest way to get from Pittsburgh to Indianapolis, IN is to drive which takes 6h 11m and costs $65 - $95.
Yes, there is a direct bus departing from Pittsburgh Intermodal Station station and arriving at Indianapolis. Services depart once daily, and operate every day. The journey takes approximately 7h 15m.
No, there is no direct train from Pittsburgh station to Indianapolis, IN. However, there are services departing from Pittsburgh Amtrak Station and arriving at Indianapolis via Chicago Union Station. The journey, including transfers, takes approximately 15h 40m.
The distance between Pittsburgh and Indianapolis, IN is 361 miles. The road distance is 360.2 miles.
The best way to get from Pittsburgh to Indianapolis, IN without a car is to bus via Indianapolis which takes 7h 31m and costs $50 - $85.
The bus from Pittsburgh Intermodal Station to Indianapolis takes 7h 15m including transfers and departs once daily.
Pittsburgh to Indianapolis, IN bus services, operated by Flixbus USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Indianapolis, IN train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Indianapolis, IN is to bus via Indianapolis which takes 7h 31m and costs $50 - $85. Alternatively, you can train, which costs $180 - $410 and takes 15h 40m, you could also fly, which costs $450 - $1,000 and takes 6h 54m.
What companies run services between Pittsburgh, PA, USA and Indianapolis, IN, USA?
Flixbus USA operates a bus from Pittsburgh Intermodal Station to Indianapolis once daily. Tickets cost $50–85 and the journey takes 7h 15m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Indianapolis via Chicago Union Station in around 15h 40m.
- Website
- united.com
Flights from Pittsburgh International Airport to Indianapolis via Washington Dulles
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $120–650
Flights from Pittsburgh International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $110–650
- Website
- delta.com
Flights from Pittsburgh International Airport to Indianapolis via Detroit
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $95–600
Flights from Pittsburgh International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $110–650
- Website
- southwest.com
Flights from Pittsburgh International Airport to Indianapolis via Chicago Midway
- Ave. Duration
- 3h 33m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Pittsburgh International Airport to Indianapolis via Baltimore
- Ave. Duration
- 6h 2m
- When
- Saturday
- Estimated price
- $120–700
Flights from Pittsburgh International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 20m
- When
- Saturday
- Estimated price
- $120–700
Flights from Pittsburgh International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 45m
- When
- Sunday
- Estimated price
- $130–750
- Website
- aa.com
Flights from Pittsburgh International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $110–650
Flights from Pittsburgh International Airport to Indianapolis via Reagan Washington
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $120–650
- Website
- flybreeze.com
Flights from Pittsburgh International Airport to Louisville International Airport
- Ave. Duration
- 1h 23m
- When
- Monday and Friday
- Estimated price
- $230–1,500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $130–290
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $50–120
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Pittsburgh Intermodal Station to Indianapolis
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $50–85
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Indianapolis Union Station
- Ave. Duration
- 7h 50m
- Frequency
- 3 times a day
- Estimated price
- $50–100
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
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More Questions & Answers
Pittsburgh to Indianapolis, IN bus services, operated by Flixbus USA, arrive at Indianapolis station.
Pittsburgh to Indianapolis, IN train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Pittsburgh to Indianapolis, IN is 360 miles. It takes approximately 6h 11m to drive from Pittsburgh to Indianapolis, IN.
Book your Pittsburgh to Indianapolis, IN train tickets online with Omio.
Book your Pittsburgh to Indianapolis, IN bus tickets online with Omio and FlixBus.
There are 883+ hotels available in Indianapolis, IN.







