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How to get fromPittsburgh to Kirksvilleby plane, train (Amtrak), bus, train, car, or shuttle

Find Transport to Kirksville

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There are 10 ways to get from Pittsburgh to Kirksville by plane, train (Amtrak), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pittsburgh International Airport to Kirksville Regional Airport

    best
    1. Fly from Pittsburgh International Airport (PIT) to Kirksville Regional Airport (IRK)plane plane PIT - IRK
    6h 47m
    $115–517

  2. Fly Pittsburgh International Airport to Burlington Municipal Airport, drive

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Burlington Municipal Airport (BRL)plane plane PIT - BRL
    2. Drive from Burlington Municipal Airport (BRL) to Kirksvillecar car
    9h 19m
    $105–498

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to La Plata Stationtrain train Southwest Chief
    15h 55m
    $458–713

  4. Bus, train

    1. Take the bus from Pittsburgh Intermodal Station to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Galesburgbus bus
    3. Take the train from Galesburg Amtrak Station to La Plata Stationtrain train
    17h 10m
    $218–339

  5. Drive  745.5 mi

    1. Drive from Pittsburgh to Kirksvillecar car 745.5 mi
    13h 14m
    $132–191

  6. Fly Pittsburgh International Airport to Lambert–St. Louis International Airport, shuttle

    1. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    2. Take a shuttle bus from St. Louis to Bowling Green, Moshuttle bus
    3. Take a shuttle bus from Bowling Green, Mo to Columbiashuttle bus
    4. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    11h 15m
    $126–653

  7. Fly Pittsburgh International Airport to Chicago Midway International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    2. Take the train from Chicago Union Station to La Plata Stationtrain train
    10h 43m
    $272–768

  8. Fly Pittsburgh International Airport to Chicago O'Hare International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    2. Take the train from Chicago Union Station to La Plata Stationtrain train
    11h 10m
    $255–647

  9. Bus to Akron, fly to Kirksville Regional Airport

    1. Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Kirksville Regional Airport (IRK)plane plane CAK - IRK
    12h 5m
    $110–440

  10. Bus, train via Chicago

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    2. Take the train from Chicago Union Station to La Plata Stationtrain train Southwest Chief
    18h 28m
    $288–443

Pittsburgh International Airport (PIT) to Kirksville Regional Airport (IRK) flights

Calendar21Weekly Planes
Duration5h 58mAverage Duration
Ticket$91Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Kirksville.ExpandLaunch map view
  • Distance: 680.9 mi
  • Duration: 6h 47m

What companies run services between Pittsburgh, PA, USA and Kirksville, MO, USA?

American Airlines, Corporate Flight Management Inc, and two other airlines fly from Pittsburgh International Airport (PIT) to Kirksville Regional Airport (IRK) 3 times a day. Alternatively, you can take a train from Pittsburgh Amtrak Station to Kirksville via Chicago Union Station and La Plata Station in around 15h 55m.

Airlines
Train operators
Bus operators

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