Rome2Rio

How to get fromPittsburgh to Knoxvilleby bus (Greyhound), train (Amtrak), car, bus, plane, taxi, subway, or train

Find Transport to Knoxville

See all options

There are 5 ways to get from Pittsburgh to Knoxville by bus (Greyhound), train (Amtrak), car, bus, plane, taxi, subway, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Pittsburgh Intermodal Station to Frederick Bus Stationbus bus Greyhound US0430 / ...
    4h 53m
    $35–63

  2. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Harpers Ferry Amtraktrain train Floridian
    6h 21m
    $90–174

  3. Drive 186.9 mi

    1. Drive from Pittsburgh to Knoxvillecar car 186.9 mi
    3h 55m
    $35–50

  4. Bus, fly to Washington Dulles International Airport, line 391 bus, taxi

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Washington Dulles International Airport (IAD)plane plane PIT - IAD
    3. Take the bus from Ashburn Metro Station - South Bus Bay to Harmony Park and Ridebus bus
    4. Take the taxi from Harmony Park and Ride to Knoxvilletaxi taxi
    5h 4m

  5. Bus, fly to Ronald Reagan Washington National Airport, subway, train

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Ronald Reagan Washington National Airport (DCA)plane plane PIT - DCA
    3. Take the subway from Gallery Place, Red Line Track 2 Platform to Rockville, Red Line Center Platformsubway subway
    4. Take the train from ROCKVILLE MARC wb to BRUNSWICK MD MARC wbtrain train
    6h 26m

Pittsburgh International Airport (PIT) to Washington Dulles International Airport (IAD) flights

Calendar28Weekly Planes
Duration1h 7mAverage Duration
Ticket$46Cheapest Price
See schedules

Questions & Answers

Map of how to get from Pittsburgh to Knoxville.ExpandLaunch map view
  • Distance: 211.8 mi
  • Duration: 4h 53m

What companies run services between Pittsburgh, PA, USA and Knoxville, MD, USA?

Greyhound USA operates a bus from Pittsburgh Intermodal Station to Frederick Bus Station every 4 hours. Tickets cost $29–60 and the journey takes 3h 30m. Alternatively, Amtrak operates a train from Pittsburgh Amtrak Station to Harpers Ferry Amtrak once daily. Tickets cost $75–160 and the journey takes 6h 11m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers