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How to get fromPittsburgh to La Crosseby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus)

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There are 8 ways to get from Pittsburgh to La Crosse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pittsburgh International Airport to La Crosse

    best
    1. Fly from Pittsburgh International Airport (PIT) to La Crosse (LSE)plane plane PIT - LSE
    6h 46m
    $102–448

  2. Bus to Morgantown Municipal Airport, fly to La Crosse

    cheapest
    1. Take the bus from Pittsburgh Greyhound to Westover Terminalbus bus
    2. Fly from Morgantown Municipal Airport (MGW) to La Crosse (LSE)plane plane MGW - LSE
    13h 51m
    $93–434

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    15h 45m
    $246–502

  4. Bus via Milwaukee

    1. Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    17h 42m
    $147–255

  5. Drive 741.4 mi

    1. Drive from Pittsburgh to La Crossecar car 741.4 mi
    12h 16m
    $136–196

  6. Bus to Akron, fly to La Crosse

    1. Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to La Crosse (LSE)plane plane CAK - LSE
    10h 59m
    $121–433

  7. Fly Pittsburgh International Airport to Minneapolis–Saint Paul International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Minneapolis–Saint Paul International Airport (MSP)plane plane PIT - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    8h 50m
    $542–1,057

  8. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    19h 55m
    $152–256

Pittsburgh to La Crosse by train (Amtrak)

Calendar7Weekly Trains
Duration15h 45mAverage Duration
Ticket$246Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to La Crosse.ExpandLaunch map view
  • Distance: 642.2 mi
  • Duration: 6h 46m

What companies run services between Pittsburgh, PA, USA and La Crosse, WI, USA?

American Airlines, Allegiant Air, and United Airlines fly from Pittsburgh International Airport (PIT) to La Crosse (LSE) every 4 hours. Alternatively, you can take a train from Pittsburgh Amtrak Station to La Crosse Amtrak Station via Chicago Union Station in around 15h 45m.

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