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How to get fromPittsburgh to Lake Cityby bus, plane, bus (Greyhound, Flixbus), train, or car

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There are 8 ways to get from Pittsburgh to Lake City by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Jacksonville, bus

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Jacksonville (JAX)plane plane PIT - JAX
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    7h 45m

  2. Bus to Akron, fly to Jacksonville, bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Jacksonville (JAX)plane plane CAK - JAX
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    10h 24m
    $99–707

  3. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    21h 50m
    $158–282

  4. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Jacksonvilletrain train Floridian
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus Greyhound US0760S
    28h 1m
    $362–728

  5. Drive 874.6 mi

    1. Drive from Pittsburgh to Lake Citycar car 874.6 mi
    14h 59m
    $160–231

  6. Fly Pittsburgh International Airport to Gainesville Regional Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Gainesville Regional Airport (GNV)plane plane PIT - GNV
    2. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    10h 47m
    $103–474

  7. Fly Pittsburgh International Airport to Orlando, bus

    1. Fly from Pittsburgh International Airport (PIT) to Orlando (MCO)plane plane PIT - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    10h 53m
    $286–1,064

  8. Fly Pittsburgh International Airport to Valdosta, bus

    1. Fly from Pittsburgh International Airport (PIT) to Valdosta (VLD)plane plane PIT - VLD
    2. Take the bus from Valdosta to Gainesville Bus Stopbus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    11h 51m
    $127–517

Pittsburgh to Lake City by bus

Calendar5Weekly Buses
Duration21h 50mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Lake City.ExpandLaunch map view
  • Distance: 799.2 mi
  • Duration: 7h 45m

What companies run services between Pittsburgh, PA, USA and Lake City, FL, USA?

You can take a bus from Pittsburgh Intermodal Station to Lake City Bus Station via Washington Union Station and Jacksonville in around 21h 50m.

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