Rome2Rio

How to get fromPittsburgh to Lake Cityby bus, plane, bus (Greyhound, Flixbus), train, or car

Find Transport to Lake City

See all options

There are 9 ways to get from Pittsburgh to Lake City by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Jacksonville, bus

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Jacksonville (JAX)plane plane PIT - JAX
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    7h 56m

  2. Fly Pittsburgh International Airport to Gainesville Regional Airport, bus

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Gainesville Regional Airport (GNV)plane plane PIT - GNV
    2. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    10h 57m
    $104–501

  3. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    21h 55m
    $141–250

  4. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Jacksonvilletrain train Floridian
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus Greyhound US0760S
    28h 6m
    $299–654

  5. Drive  874.6 mi

    1. Drive from Pittsburgh to Lake Citycar car 874.6 mi
    14h 59m
    $160–231

  6. Fly Pittsburgh International Airport to Orlando, bus

    1. Fly from Pittsburgh International Airport (PIT) to Orlando (MCO)plane plane PIT - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    10h 53m
    $284–739

  7. Bus to Akron, fly to Jacksonville, bus

    1. Take the bus from Pittsburgh Intermodal Station to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Jacksonville (JAX)plane plane CAK - JAX
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    10h 34m
    $115–540

  8. Fly Pittsburgh International Airport to Valdosta, bus

    1. Fly from Pittsburgh International Airport (PIT) to Valdosta (VLD)plane plane PIT - VLD
    2. Take the bus from Valdosta to Gainesville Bus Stopbus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    11h 31m
    $125–536

  9. Fly Pittsburgh International Airport to Orlando Sanford, drive

    1. Fly from Pittsburgh International Airport (PIT) to Orlando Sanford (SFB)plane plane PIT - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Lake Citycar car
    7h 24m
    $127–545

Pittsburgh to Lake City by bus

Calendar9Weekly Buses
Duration21h 55mAverage Duration
Ticket$141Cheapest Price
See schedules

Questions & Answers

Map of how to get from Pittsburgh to Lake City.ExpandLaunch map view
  • Distance: 799.2 mi
  • Duration: 7h 56m

What companies run services between Pittsburgh, PA, USA and Lake City, FL, USA?

You can take a bus from Pittsburgh Intermodal Station to Lake City Bus Station via Washington Union Station and Jacksonville in around 21h 55m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers