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How to get fromPittsburgh to Lexingtonby plane, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Lexington

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There are 6 ways to get from Pittsburgh to Lexington by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia

    best
    1. Fly from Pittsburgh International Airport (PIT) to Columbia (CAE)plane plane PIT - CAE
    6h
    $196–970

  2. Drive 542.3 mi

    cheapest
    1. Drive from Pittsburgh to Lexingtoncar car 542.3 mi
    9h 27m
    $99–143

  3. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    3. Take the bus from S Saunders St at Chapanoke Rd - Raleigh to Columbia, SCbus bus Nyc
    16h 35m
    $152–256

  4. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Raleigh Union Stationtrain train Floridian
    2. Take the bus from S Saunders St at Chapanoke Rd - Raleigh to Columbia, SCbus bus Nyc
    20h 19m
    $265–488

  5. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Lexingtoncar car
    5h 33m
    $119–598

  6. Fly to Charleston International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    2. Drive from Charleston-Airport-CHS to Lexingtoncar car
    5h 52m
    $101–465

Pittsburgh International Airport (PIT) to Columbia (CAE) flights

Calendar155Weekly Planes
Duration5h 14mAverage Duration
Ticket$167Cheapest Price
See schedules

Questions & Answers

Map of how to get from Pittsburgh to Lexington.ExpandLaunch map view
  • Distance: 488.9 mi
  • Duration: 6h

What companies run services between Pittsburgh, PA, USA and Lexington, SC, USA?

American Airlines, United Airlines, and Delta fly from Pittsburgh International Airport (PIT) to Columbia (CAE) hourly. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Lexington via Washington Union Station, Raleigh Bus Station, Capital Blvd at Crabtree Blvd, GoRaleigh Station, S Saunders St at Chapanoke Rd - Raleigh, and Columbia, SC in around 16h 35m.

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