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How to get fromPittsburgh to Lexingtonby plane, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Lexington

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There are 6 ways to get from Pittsburgh to Lexington by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia

    best
    1. Fly from Pittsburgh International Airport (PIT) to Columbia (CAE)plane plane PIT - CAE
    5h 53m
    $101–465

  2. Drive  542.3 mi

    cheapest
    1. Drive from Pittsburgh to Lexingtoncar car 542.3 mi
    9h 27m
    $99–143

  3. Bus

    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    3. Take the bus from S Saunders St at Chapanoke Rd - Raleigh to Columbia, SCbus bus Nyc
    16h 50m
    $151–237

  4. Train, bus

    1. Take the train from Pittsburgh Amtrak Station to Raleigh Union Stationtrain train Floridian
    2. Take the bus from S Saunders St at Chapanoke Rd - Raleigh to Columbia, SCbus bus Nyc
    20h 25m
    $401–606

  5. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Greenville–Spartanburg International Airport (GSP)plane plane PIT - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Lexingtoncar car
    5h 38m
    $130–697

  6. Fly to Charleston International Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Charleston International Airport (CHS)plane plane PIT - CHS
    2. Drive from Charleston-Airport-CHS to Lexingtoncar car
    5h 54m
    $115–570

Pittsburgh International Airport (PIT) to Columbia (CAE) flights

Calendar129Weekly Planes
Duration4h 25mAverage Duration
Ticket$72Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Pittsburgh to Lexington.ExpandLaunch map view
  • Distance: 488.9 mi
  • Duration: 5h 53m

What companies run services between Pittsburgh, PA, USA and Lexington, SC, USA?

American Airlines, United Airlines, and Delta fly from Pittsburgh International Airport (PIT) to Columbia (CAE) hourly. Alternatively, you can take a bus from Pittsburgh Intermodal Station to Lexington via Washington Union Station, Raleigh Bus Station, Capital Blvd at Crabtree Blvd, GoRaleigh Station, S Saunders St at Chapanoke Rd - Raleigh, and Columbia, SC in around 16h 50m.

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