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How to get fromPittsburgh to Louisvilleby bus, plane, bus (Greyhound), car, or bus (Flixbus)

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There are 6 ways to get from Pittsburgh to Louisville by bus, plane, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Louisville International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane plane PIT - SDF
    4h 53m

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus Greyhound US0421
    2. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus Cleveland
    8h 45m
    $50–114

  3. Drive 385.5 mi

    1. Drive from Pittsburgh to Louisvillecar car 385.5 mi
    6h 37m
    $71–102

  4. Fly to Blue Grass Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Blue Grass Airport (LEX)plane plane PIT - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    7h 4m
    $160–841

  5. Bus via Columbus

    1. Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus bus Greyhound US0421
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus bus Cleveland
    9h 10m
    $50–116

  6. Bus #2

    1. Take the bus from Pittsburgh Intermodal Station to Cincinnatibus bus FlixBus N2642
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus Cleveland
    9h 47m
    $59–128

Pittsburgh to Louisville by bus

Calendar14Weekly Buses
Duration8h 45mAverage Duration
Ticket$50Cheapest Price
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Questions & Answers

Map of how to get from Pittsburgh to Louisville.ExpandLaunch map view
  • Distance: 365.2 mi
  • Duration: 4h 53m

What companies run services between Pittsburgh, PA, USA and Louisville, KY, USA?

You can take a bus from Pittsburgh Intermodal Station to Louisville, KY Bus Station via Columbus - Downtown - Mound St in around 8h 45m.

Airlines
Bus operators

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