Rome2Rio

How to get fromPittsburgh to Louisvilleby bus, plane, bus (Greyhound), car, or bus (Flixbus)

Find Transport to Louisville

See all options

There are 6 ways to get from Pittsburgh to Louisville by bus, plane, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Louisville International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane plane PIT - SDF
    4h 47m

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus Greyhound US0421
    2. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus Cleveland
    8h 45m
    $47–109

  3. Drive 385.5 mi

    1. Drive from Pittsburgh to Louisvillecar car 385.5 mi
    6h 37m
    $71–102

  4. Fly to Blue Grass Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Blue Grass Airport (LEX)plane plane PIT - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    7h 3m
    $86–435

  5. Bus via Columbus

    1. Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus bus Greyhound US0421
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus bus Cleveland
    9h 10m
    $47–111

  6. Bus #2

    1. Take the bus from Pittsburgh Intermodal Station to Cincinnatibus bus FlixBus N2642
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus Cleveland
    9h 47m
    $54–119

Pittsburgh to Louisville by bus

Calendar14Weekly Buses
Duration8h 45mAverage Duration
Ticket$47Cheapest Price
See schedules

Questions & Answers

Map of how to get from Pittsburgh to Louisville.ExpandLaunch map view
  • Distance: 365.2 mi
  • Duration: 4h 47m

What companies run services between Pittsburgh, PA, USA and Louisville, KY, USA?

You can take a bus from Pittsburgh Intermodal Station to Louisville, KY Bus Station via Columbus - Downtown - Mound St in around 8h 45m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers