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How to get fromPittsburgh to Louisvilleby bus (Greyhound, Amtrak), car, plane, or bus

Find Transport to Louisville

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There are 5 ways to get from Pittsburgh to Louisville by bus (Greyhound, Amtrak), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Pittsburgh Intermodal Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    10h 45m
    $81–137

  2. Drive  385.5 mi

    cheapest
    1. Drive from Pittsburgh to Louisvillecar car 385.5 mi
    6h 37m
    $71–102

  3. Fly to Blue Grass Airport, drive

    1. Fly from Pittsburgh International Airport (PIT) to Blue Grass Airport (LEX)plane plane PIT - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    7h 20m
    $87–452

  4. Bus, fly to Louisville International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane plane PIT - SDF
    4h 47m

  5. Fly to Nashville, bus

    1. Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane plane PIT - BNA
    2. Take the bus from Nashville to Louisville, KYbus bus
    9h 4m
    $552–1,065

Pittsburgh to Louisville by bus

Calendar14Weekly Buses
Duration10h 45mAverage Duration
Ticket$81Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pittsburgh to Louisville.ExpandLaunch map view
  • Distance: 481.5 mi
  • Duration: 10h 45m

What companies run services between Pittsburgh, PA, USA and Louisville, KY, USA?

You can take a bus from Pittsburgh Intermodal Station to Louisville, KY via Indianapolis Union Station in around 10h 45m.

Airlines
Bus operators

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