There are 8 ways to get from Pittsburgh to Louisville by bus (Greyhound), car, plane, bus (Flixbus), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Pittsburgh Intermodal Station to Columbusbus Greyhound US0421
- Take the bus from Columbus to Louisvillebus Bsb 27 / ...
8h 35m$64–101Bus via Columbus
cheapest- Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus Greyhound US0421
- Take the bus from Columbus to Louisvillebus Bsb 27 / ...
9h 5m$51–108Drive 385.5 mi
- Drive from Pittsburgh to Louisvillecar 385.5 mi
6h 37m$71–102Fly to Blue Grass Airport, drive
- Fly from Pittsburgh International Airport (PIT) to Blue Grass Airport (LEX)plane PIT - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
7h 20m$87–452Bus #2
- Take the bus from Pittsburgh Intermodal Station to Cincinnatibus FlixBus N2642
- Take the bus from Cincinnati to Louisvillebus Bsb 27 / ...
9h 40m$57–119Bus, fly to Louisville International Airport
- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane PIT - SDF
4h 47mFly to Covington, bus
- Fly from Pittsburgh International Airport (PIT) to Covington (CVG)plane PIT - CVG
- Take the bus from Cincinnati to Louisvillebus
9h 40m$124–730Fly to Nashville, bus
- Fly from Pittsburgh International Airport (PIT) to Nashville (BNA)plane PIT - BNA
- Take the bus from Nashville Bus Station to Louisville Bus Stationbus
8h 34m$548–1,060
Pittsburgh to Louisville by bus
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Louisville is to bus which costs $60 - $110 and takes 8h 35m.
The fastest way to get from Pittsburgh to Louisville is to drive which takes 6h 37m and costs $70 - $110.
No, there is no direct bus from Pittsburgh station to Louisville. However, there are services departing from Pittsburgh Intermodal Station and arriving at Louisville via Columbus. The journey, including transfers, takes approximately 8h 35m.
The distance between Pittsburgh and Louisville is 400 miles. The road distance is 387.8 miles.
The best way to get from Pittsburgh to Louisville without a car is to bus which takes 8h 35m and costs $60 - $110.
It takes approximately 8h 35m to get from Pittsburgh to Louisville, including transfers.
Pittsburgh to Louisville bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Louisville bus services, operated by Greyhound USA, arrive at Columbus station.
Yes, the driving distance between Pittsburgh to Louisville is 388 miles. It takes approximately 6h 37m to drive from Pittsburgh to Louisville.
Book your Pittsburgh to Louisville bus tickets online with Omio and FlixBus.
What companies run services between Pittsburgh, PA, USA and Louisville, KY, USA?
You can take a bus from Pittsburgh Intermodal Station to Louisville via Columbus in around 8h 35m.
- Website
- southwest.com
Flights from Pittsburgh International Airport to Covington via Chicago Midway
- Ave. Duration
- 6h 56m
- When
- Sunday, Tuesday, Wednesday, Monday, Thursday, and Friday
- Estimated price
- $140–800
Flights from Pittsburgh International Airport to Covington via Nashville
- Ave. Duration
- 7h 8m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Pittsburgh International Airport to Covington via Baltimore
- Ave. Duration
- 6h 16m
- When
- Sunday, Tuesday, Wednesday, Monday, Thursday, and Friday
- Estimated price
- $130–800
Flights from Pittsburgh International Airport to Nashville
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $80–490
Flights from Pittsburgh International Airport to Nashville via Chicago Midway
- Ave. Duration
- 3h 47m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $110–600
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Columbus
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a day
- Estimated price
- $29–50
- Website
- Greyhound
Bus from Columbus to Louisville
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbus
- Ave. Duration
- 4h 5m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Nashville Bus Station to Louisville Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Every 4 hours
- Estimated price
- $28–45
- Website
- Greyhound
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Booking & Getting There
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